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SIRT2 inhibitor SirReal2 enhances anti‐tumor effects of PI3K/mTOR inhibitor VS‐5584 on acute myeloid leukemia cells

BACKGROUND: Acute myeloid leukemia (AML) is a highly aggressive form of cancer that is frequently diagnosed in adults and small molecule inhibitors have gained significant attention as a potential treatment option for AML. METHODS: The up‐regulated genes in AML were identified through bioinformatics...

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Detalles Bibliográficos
Autores principales: Luo, Yiming, Zhao, Haijun, Zhu, Jingtao, Zhang, Liyi, Zha, Jie, Zhang, Li, Ding, Yi, Jian, Xinyi, Xia, Junjie, Xu, Bing, Qi, Zhongquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557894/
https://www.ncbi.nlm.nih.gov/pubmed/37658623
http://dx.doi.org/10.1002/cam4.6480