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Cobertura vacunal, creencias y actitudes en niños y adolescentes trasplantados: una revisión sistemática de métodos mixtos

BACKGROUND: Vaccine-preventable infectious diseases are a cause of morbidity and mortality in transplanted children. The main objective of this study was to synthesize the available evidence of vaccination coverage in children and adolescents who are candidates or transplant recipients and to analyz...

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Autores principales: Herrero-Diez, María Teresa, Catalá-López, Ferrán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ministerio de Sanidad 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558112/
https://www.ncbi.nlm.nih.gov/pubmed/36999242
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author Herrero-Diez, María Teresa
Catalá-López, Ferrán
author_facet Herrero-Diez, María Teresa
Catalá-López, Ferrán
author_sort Herrero-Diez, María Teresa
collection PubMed
description BACKGROUND: Vaccine-preventable infectious diseases are a cause of morbidity and mortality in transplanted children. The main objective of this study was to synthesize the available evidence of vaccination coverage in children and adolescents who are candidates or transplant recipients and to analyze beliefs, attitudes, and experiences about vaccination. METHODS: A mixed-methods systematic review was performed (Open Science Framework registration: https://osf.io/auqn3/). Searches were conducted in PubMed/MEDLINE, EMBASE, IBECS and LILACS (from January 2000 to August 2021) and in gray literature. Quantitative and qualitative studies reported information on coverage, beliefs, attitudes and/or experiences about recommended vaccines in children who are candidates or recipients of solid organ or hematopoietic progenitor transplantation. Quality assessment was undertaken using Mixed Methods Appraisal Tool (MMAT). A narrative synthesis of the studies was carried out. RESULTS: A total of thirty-two studies in thirty-five publications were included. The most studied interventions were vaccines against measles (n=21; 66%) and hepatitis B (n=20; 62%). Vaccination rates showed a high variability for the most represented vaccines (specifically, 2%-100% for measles, 0.4%-100% for hepatitis B, diphtheria-tetanus-pertussis and rubella), with coverages lower than 90% in at least 70% of the studies. The lowest rates were reported in post-transplantation and hematopoietic stem cell transplantation. Only one qualitative study was identified reporting information on beliefs and/or attitudes, although nine quantitative studies explored cognitive aspects. CONCLUSIONS: This review shows a high variability in vaccination coverage in children and adolescents who are transplant candidates or recipients, with rates lower than those recommended. Further studies would be needed to identify beliefs and attitudes about immunization in this context.
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spelling pubmed-105581122023-10-07 Cobertura vacunal, creencias y actitudes en niños y adolescentes trasplantados: una revisión sistemática de métodos mixtos Herrero-Diez, María Teresa Catalá-López, Ferrán Rev Esp Salud Publica Revisión Sistemática BACKGROUND: Vaccine-preventable infectious diseases are a cause of morbidity and mortality in transplanted children. The main objective of this study was to synthesize the available evidence of vaccination coverage in children and adolescents who are candidates or transplant recipients and to analyze beliefs, attitudes, and experiences about vaccination. METHODS: A mixed-methods systematic review was performed (Open Science Framework registration: https://osf.io/auqn3/). Searches were conducted in PubMed/MEDLINE, EMBASE, IBECS and LILACS (from January 2000 to August 2021) and in gray literature. Quantitative and qualitative studies reported information on coverage, beliefs, attitudes and/or experiences about recommended vaccines in children who are candidates or recipients of solid organ or hematopoietic progenitor transplantation. Quality assessment was undertaken using Mixed Methods Appraisal Tool (MMAT). A narrative synthesis of the studies was carried out. RESULTS: A total of thirty-two studies in thirty-five publications were included. The most studied interventions were vaccines against measles (n=21; 66%) and hepatitis B (n=20; 62%). Vaccination rates showed a high variability for the most represented vaccines (specifically, 2%-100% for measles, 0.4%-100% for hepatitis B, diphtheria-tetanus-pertussis and rubella), with coverages lower than 90% in at least 70% of the studies. The lowest rates were reported in post-transplantation and hematopoietic stem cell transplantation. Only one qualitative study was identified reporting information on beliefs and/or attitudes, although nine quantitative studies explored cognitive aspects. CONCLUSIONS: This review shows a high variability in vaccination coverage in children and adolescents who are transplant candidates or recipients, with rates lower than those recommended. Further studies would be needed to identify beliefs and attitudes about immunization in this context. Ministerio de Sanidad 2023-03-30 /pmc/articles/PMC10558112/ /pubmed/36999242 Text en https://creativecommons.org/licenses/by-nc-nd/3.0/Este es un artículo publicado en acceso abierto bajo una licencia Creative Commons
spellingShingle Revisión Sistemática
Herrero-Diez, María Teresa
Catalá-López, Ferrán
Cobertura vacunal, creencias y actitudes en niños y adolescentes trasplantados: una revisión sistemática de métodos mixtos
title Cobertura vacunal, creencias y actitudes en niños y adolescentes trasplantados: una revisión sistemática de métodos mixtos
title_full Cobertura vacunal, creencias y actitudes en niños y adolescentes trasplantados: una revisión sistemática de métodos mixtos
title_fullStr Cobertura vacunal, creencias y actitudes en niños y adolescentes trasplantados: una revisión sistemática de métodos mixtos
title_full_unstemmed Cobertura vacunal, creencias y actitudes en niños y adolescentes trasplantados: una revisión sistemática de métodos mixtos
title_short Cobertura vacunal, creencias y actitudes en niños y adolescentes trasplantados: una revisión sistemática de métodos mixtos
title_sort cobertura vacunal, creencias y actitudes en niños y adolescentes trasplantados: una revisión sistemática de métodos mixtos
topic Revisión Sistemática
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558112/
https://www.ncbi.nlm.nih.gov/pubmed/36999242
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