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Deficient chaperone-mediated autophagy facilitates LPS-induced microglial activation via regulation of the p300/NF-κB/NLRP3 pathway

Neuroinflammation is a pathological change that is involved in the progression of Parkinson’s disease. Dysfunction of chaperone-mediated autophagy (CMA) has proinflammatory effects. However, the mechanism by which CMA mediates inflammation and whether CMA affects microglia and microglia-mediated neu...

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Detalles Bibliográficos
Autores principales:	Wu, Jin, Han, Yingying, Xu, Hao, Sun, Hongyang, Wang, Rui, Ren, Haigang, Wang, Guanghui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2023
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558133/ https://www.ncbi.nlm.nih.gov/pubmed/37801503 http://dx.doi.org/10.1126/sciadv.adi8343

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