ERCP in patients over 90 years old: Safety and efficacy comparison with a younger cohort

Background and study aims As life expectancy increases worldwide, so does the prevalence of biliary tract and pancreatic disorders, resulting in rising demand for invasive procedures such as endoscopic retrograde cholangiopancreatography (ERCP) in the elderly. Few studies have assessed the safety of ERCP in patients 90 years and older, particularly among the Hispanic population. The primary aim of this study was to determine the technical success and adverse events (AEs) associated with ERCP in patients 90 years of age or older in comparison to a younger cohort of patients. Patients and methods A retrospective analysis of all ERCPs done at our institution from 2012 to 2018 was performed. Three hundred ERCPs in patients < 90 years old and all 28 ERCPs done in patients ≥ 90 years old were included in the analysis. Results ERCPs were successfully completed in 96.4% of patients > 90 years old and 96.3% of the < 90-year-old cohort (realtive risk [RR] 1.00, confidence interval 0.92-1.07). There was no difference in the rate of periprocedural AEs. Post-ERCP AEs occurred in 7.1% and 3.0% in patients aged < 90 and > 90 years, respectively (RR 2.38, 0.54-10.48). No deaths were directly attributed to the procedure; however, inpatient mortality was higher in the group aged > 90 years. Conclusions ERCP is safe and effective in nonagenarian patients, and advanced age should not be considered an independent risk factor for AEs nor a contraindication for the procedure.