Deconvolution reveals cell-type-specific transcriptomic changes in the aging mouse brain

Mounting evidence highlights the crucial role of aging in the pathogenesis of Alzheimer's disease (AD). We have previously explored human apoE-targeted replacement mice across different ages and identified distinct molecular pathways driven by aging. However, the specific contribution of differ...

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Detalles Bibliográficos
Autores principales: Ren, Yingxue, Wang, Xue, Zhang, Shuwen, Hu, Hongru, Quicksall, Zachary, Lee, Sangderk, Morganti, Josh M., Johnson, Lance A., Asmann, Yan W., Zhao, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558435/
https://www.ncbi.nlm.nih.gov/pubmed/37803069
http://dx.doi.org/10.1038/s41598-023-44183-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558435/
https://www.ncbi.nlm.nih.gov/pubmed/37803069
http://dx.doi.org/10.1038/s41598-023-44183-7

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