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Deconvolution reveals cell-type-specific transcriptomic changes in the aging mouse brain
Mounting evidence highlights the crucial role of aging in the pathogenesis of Alzheimer's disease (AD). We have previously explored human apoE-targeted replacement mice across different ages and identified distinct molecular pathways driven by aging. However, the specific contribution of differ...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558435/ https://www.ncbi.nlm.nih.gov/pubmed/37803069 http://dx.doi.org/10.1038/s41598-023-44183-7 |