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Catalytic enantioselective reductive alkynylation of amides enables one-pot syntheses of pyrrolidine, piperidine and indolizidine alkaloids

The primary objective in synthetic organic chemistry is to develop highly efficient, selective, and versatile synthetic methodologies, which are essential for discovering new drug candidates and agrochemicals. In this study, we present a unified strategy for a one-pot, catalytic enantioselective syn...

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Detalles Bibliográficos
Autores principales: Xu, Fang-Fang, Chen, Jin-Quan, Shao, Dong-Yang, Huang, Pei-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558451/
https://www.ncbi.nlm.nih.gov/pubmed/37803030
http://dx.doi.org/10.1038/s41467-023-41846-x