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Human cellular model systems of β-thalassemia enable in-depth analysis of disease phenotype

β-thalassemia is a prevalent genetic disorder causing severe anemia due to defective erythropoiesis, with few treatment options. Studying the underlying molecular defects is impeded by paucity of suitable patient material. In this study we create human disease cellular model systems for β-thalassemi...

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Detalles Bibliográficos
Autores principales:	Daniels, Deborah E., Ferrer-Vicens, Ivan, Hawksworth, Joseph, Andrienko, Tatyana N., Finnie, Elizabeth M., Bretherton, Natalie S., Ferguson, Daniel C. J., Oliveira, A. Sofia. F., Szeto, Jenn-Yeu A., Wilson, Marieangela C., Brewin, John N., Frayne, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558456/ https://www.ncbi.nlm.nih.gov/pubmed/37803026 http://dx.doi.org/10.1038/s41467-023-41961-9

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