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Combination therapy of tyrosine kinase inhibitor sorafenib with the HSP90 inhibitor onalespib as a novel treatment regimen for thyroid cancer
Thyroid cancer is the most common endocrine malignancy, affecting nearly 600,000 new patients worldwide. Treatment with the BRAF inhibitor sorafenib partially prolongs progression-free survival in thyroid cancer patients, but fails to improve overall survival. This study examines enhancing sorafenib...
Autores principales: | Mortensen, Anja Charlotte Lundgren, Berglund, Hanna, Hariri, Mehran, Papalanis, Eleftherios, Malmberg, Christer, Spiegelberg, Diana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558458/ https://www.ncbi.nlm.nih.gov/pubmed/37803074 http://dx.doi.org/10.1038/s41598-023-43486-z |
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