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The endoribonuclease Arlr is required to maintain lipid homeostasis by downregulating lipolytic genes during aging
While disorders in lipid metabolism have been associated with aging and age-related diseases, how lipid metabolism is regulated during aging is poorly understood. Here, we characterize the Drosophila endoribonuclease CG2145, an ortholog of mammalian EndoU that we named Age-related lipid regulator (A...
Autores principales: | Sun, Xiaowei, Shen, Jie, Perrimon, Norbert, Kong, Xue, Wang, Dan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558556/ https://www.ncbi.nlm.nih.gov/pubmed/37803019 http://dx.doi.org/10.1038/s41467-023-42042-7 |
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