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The endoribonuclease Arlr is required to maintain lipid homeostasis by downregulating lipolytic genes during aging

While disorders in lipid metabolism have been associated with aging and age-related diseases, how lipid metabolism is regulated during aging is poorly understood. Here, we characterize the Drosophila endoribonuclease CG2145, an ortholog of mammalian EndoU that we named Age-related lipid regulator (A...

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Detalles Bibliográficos
Autores principales: Sun, Xiaowei, Shen, Jie, Perrimon, Norbert, Kong, Xue, Wang, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558556/
https://www.ncbi.nlm.nih.gov/pubmed/37803019
http://dx.doi.org/10.1038/s41467-023-42042-7

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