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Characteristics and in-hospital mortality of patients with COVID-19 from the first to fifth waves of the pandemic in 2020 and 2021 in the Japanese Medical Data Vision database

OBJECTIVES: We aimed to describe patient characteristics, healthcare utilization, and in-hospital mortality among patients with COVID-19 in Japan across waves. METHODS: Using a large-scale hospital-based database, we identified patients hospitalized for COVID-19 in the first (January–June 2020), sec...

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Autores principales: Suzuki, Toshiki, Taniguchi, Yuta, Komiyama, Jun, Kuno, Toshiki, Adomi, Motohiko, Abe, Toshikazu, Inokuchi, Ryota, Miyawaki, Atsushi, Imai, Shinobu, Saito, Makoto, Ohbe, Hiroyuki, Aso, Shotaro, Kamio, Tadashi, Tamiya, Nanako, Iwagami, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558584/
https://www.ncbi.nlm.nih.gov/pubmed/37809807
http://dx.doi.org/10.1016/j.heliyon.2023.e19490
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author Suzuki, Toshiki
Taniguchi, Yuta
Komiyama, Jun
Kuno, Toshiki
Adomi, Motohiko
Abe, Toshikazu
Inokuchi, Ryota
Miyawaki, Atsushi
Imai, Shinobu
Saito, Makoto
Ohbe, Hiroyuki
Aso, Shotaro
Kamio, Tadashi
Tamiya, Nanako
Iwagami, Masao
author_facet Suzuki, Toshiki
Taniguchi, Yuta
Komiyama, Jun
Kuno, Toshiki
Adomi, Motohiko
Abe, Toshikazu
Inokuchi, Ryota
Miyawaki, Atsushi
Imai, Shinobu
Saito, Makoto
Ohbe, Hiroyuki
Aso, Shotaro
Kamio, Tadashi
Tamiya, Nanako
Iwagami, Masao
author_sort Suzuki, Toshiki
collection PubMed
description OBJECTIVES: We aimed to describe patient characteristics, healthcare utilization, and in-hospital mortality among patients with COVID-19 in Japan across waves. METHODS: Using a large-scale hospital-based database, we identified patients hospitalized for COVID-19 in the first (January–June 2020), second (June–October 2020), third (October 2020–February 2021), fourth (March–June 2021), and fifth (June–December 2021) waves. We summarized patient characteristics, healthcare utilization, and in-hospital mortality during each wave and performed multivariable logistic regression analyses for in-hospital mortality. RESULTS: From the first to fifth waves, the number of patients (mean age ± standard deviation, years) was 2958 (61.2 ± 22.8), 7981 (55.6 ± 25.3), 18,788 (63.6 ± 22.9), 17,729 (60.6 ± 22.6), and 23,656 (51.2 ± 22.3), respectively. There were 190 (6.4%), 363 (4.5%), 1261 (6.7%), 1081 (6.1%), and 762 (3.2%) in-hospital deaths, respectively. The adjusted odds ratios for in-hospital deaths (95% confidence interval) were 0.78 (0.65–0.95), 0.94 (0.79–1.12), 0.99 (0.84–1.18), 0.77 (0.65–0.92), in the second to fifth waves, respectively, compared with the first wave. CONCLUSIONS: In-hospital COVID-19 mortality improved from the first to the second wave; however, during the third and fourth waves, mortality was as serious as in the first wave. Although in-hospital mortality during the fifth wave improved, careful monitoring is needed for upcoming waves, considering changing patient and viral characteristics.
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spelling pubmed-105585842023-10-08 Characteristics and in-hospital mortality of patients with COVID-19 from the first to fifth waves of the pandemic in 2020 and 2021 in the Japanese Medical Data Vision database Suzuki, Toshiki Taniguchi, Yuta Komiyama, Jun Kuno, Toshiki Adomi, Motohiko Abe, Toshikazu Inokuchi, Ryota Miyawaki, Atsushi Imai, Shinobu Saito, Makoto Ohbe, Hiroyuki Aso, Shotaro Kamio, Tadashi Tamiya, Nanako Iwagami, Masao Heliyon Research Article OBJECTIVES: We aimed to describe patient characteristics, healthcare utilization, and in-hospital mortality among patients with COVID-19 in Japan across waves. METHODS: Using a large-scale hospital-based database, we identified patients hospitalized for COVID-19 in the first (January–June 2020), second (June–October 2020), third (October 2020–February 2021), fourth (March–June 2021), and fifth (June–December 2021) waves. We summarized patient characteristics, healthcare utilization, and in-hospital mortality during each wave and performed multivariable logistic regression analyses for in-hospital mortality. RESULTS: From the first to fifth waves, the number of patients (mean age ± standard deviation, years) was 2958 (61.2 ± 22.8), 7981 (55.6 ± 25.3), 18,788 (63.6 ± 22.9), 17,729 (60.6 ± 22.6), and 23,656 (51.2 ± 22.3), respectively. There were 190 (6.4%), 363 (4.5%), 1261 (6.7%), 1081 (6.1%), and 762 (3.2%) in-hospital deaths, respectively. The adjusted odds ratios for in-hospital deaths (95% confidence interval) were 0.78 (0.65–0.95), 0.94 (0.79–1.12), 0.99 (0.84–1.18), 0.77 (0.65–0.92), in the second to fifth waves, respectively, compared with the first wave. CONCLUSIONS: In-hospital COVID-19 mortality improved from the first to the second wave; however, during the third and fourth waves, mortality was as serious as in the first wave. Although in-hospital mortality during the fifth wave improved, careful monitoring is needed for upcoming waves, considering changing patient and viral characteristics. Elsevier 2023-08-25 /pmc/articles/PMC10558584/ /pubmed/37809807 http://dx.doi.org/10.1016/j.heliyon.2023.e19490 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Article
Suzuki, Toshiki
Taniguchi, Yuta
Komiyama, Jun
Kuno, Toshiki
Adomi, Motohiko
Abe, Toshikazu
Inokuchi, Ryota
Miyawaki, Atsushi
Imai, Shinobu
Saito, Makoto
Ohbe, Hiroyuki
Aso, Shotaro
Kamio, Tadashi
Tamiya, Nanako
Iwagami, Masao
Characteristics and in-hospital mortality of patients with COVID-19 from the first to fifth waves of the pandemic in 2020 and 2021 in the Japanese Medical Data Vision database
title Characteristics and in-hospital mortality of patients with COVID-19 from the first to fifth waves of the pandemic in 2020 and 2021 in the Japanese Medical Data Vision database
title_full Characteristics and in-hospital mortality of patients with COVID-19 from the first to fifth waves of the pandemic in 2020 and 2021 in the Japanese Medical Data Vision database
title_fullStr Characteristics and in-hospital mortality of patients with COVID-19 from the first to fifth waves of the pandemic in 2020 and 2021 in the Japanese Medical Data Vision database
title_full_unstemmed Characteristics and in-hospital mortality of patients with COVID-19 from the first to fifth waves of the pandemic in 2020 and 2021 in the Japanese Medical Data Vision database
title_short Characteristics and in-hospital mortality of patients with COVID-19 from the first to fifth waves of the pandemic in 2020 and 2021 in the Japanese Medical Data Vision database
title_sort characteristics and in-hospital mortality of patients with covid-19 from the first to fifth waves of the pandemic in 2020 and 2021 in the japanese medical data vision database
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558584/
https://www.ncbi.nlm.nih.gov/pubmed/37809807
http://dx.doi.org/10.1016/j.heliyon.2023.e19490
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