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Bubble plastic use in rats hernioplasty: Uso do plástico bolha em hernioplastias de ratos
PURPOSE: Despite the high frequency of hernioplasties worldwide, their complications and recurrences are still a challenge to be overcome. The search for prostheses that aim to promote the correction of hernia defects has been a challenge. For this purpose, the materials used in hernioplasties must...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558621/ https://www.ncbi.nlm.nih.gov/pubmed/37809872 http://dx.doi.org/10.1016/j.heliyon.2023.e19483 |
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author | da Fonseca Jorge, Siria Seabra da Costa, Carolina de Brito Gitirana, Lycia Abidu Figueiredo, Marcelo |
author_facet | da Fonseca Jorge, Siria Seabra da Costa, Carolina de Brito Gitirana, Lycia Abidu Figueiredo, Marcelo |
author_sort | da Fonseca Jorge, Siria |
collection | PubMed |
description | PURPOSE: Despite the high frequency of hernioplasties worldwide, their complications and recurrences are still a challenge to be overcome. The search for prostheses that aim to promote the correction of hernia defects has been a challenge. For this purpose, the materials used in hernioplasties must be biocompatible, promote the formation of little or no peritoneal adhesion, possess compatible texture and flexibility, providing the necessary resistance to protect the viscera and allow the movement of the abdomen. METHODS: The aim of the present study was to evaluate the effectiveness of bubble plastic (low density polyethylene, LDPE) as a material for the correction of hernia in the abdominal wall. For this, twenty male rats (Rattus norvegicus, Wistar variety) were used and divided into four groups of five animals. The animals were evaluated at 7, 15, 30 and 90 days after surgery according to clinical, thermographic and morphological parameters (macroscopic and microscopic). RESULTS: The results showed that the bubble plastic induced inflammatory reaction in the initial period (7 day), followed by a reduction (30 day) to increase considerably at 90 days after the operation. CONCLUSION: So, bubble plastic can be used for temporary implants (up to 30 days). |
format | Online Article Text |
id | pubmed-10558621 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-105586212023-10-08 Bubble plastic use in rats hernioplasty: Uso do plástico bolha em hernioplastias de ratos da Fonseca Jorge, Siria Seabra da Costa, Carolina de Brito Gitirana, Lycia Abidu Figueiredo, Marcelo Heliyon Research Article PURPOSE: Despite the high frequency of hernioplasties worldwide, their complications and recurrences are still a challenge to be overcome. The search for prostheses that aim to promote the correction of hernia defects has been a challenge. For this purpose, the materials used in hernioplasties must be biocompatible, promote the formation of little or no peritoneal adhesion, possess compatible texture and flexibility, providing the necessary resistance to protect the viscera and allow the movement of the abdomen. METHODS: The aim of the present study was to evaluate the effectiveness of bubble plastic (low density polyethylene, LDPE) as a material for the correction of hernia in the abdominal wall. For this, twenty male rats (Rattus norvegicus, Wistar variety) were used and divided into four groups of five animals. The animals were evaluated at 7, 15, 30 and 90 days after surgery according to clinical, thermographic and morphological parameters (macroscopic and microscopic). RESULTS: The results showed that the bubble plastic induced inflammatory reaction in the initial period (7 day), followed by a reduction (30 day) to increase considerably at 90 days after the operation. CONCLUSION: So, bubble plastic can be used for temporary implants (up to 30 days). Elsevier 2023-08-28 /pmc/articles/PMC10558621/ /pubmed/37809872 http://dx.doi.org/10.1016/j.heliyon.2023.e19483 Text en © 2023 Published by Elsevier Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Research Article da Fonseca Jorge, Siria Seabra da Costa, Carolina de Brito Gitirana, Lycia Abidu Figueiredo, Marcelo Bubble plastic use in rats hernioplasty: Uso do plástico bolha em hernioplastias de ratos |
title | Bubble plastic use in rats hernioplasty: Uso do plástico bolha em hernioplastias de ratos |
title_full | Bubble plastic use in rats hernioplasty: Uso do plástico bolha em hernioplastias de ratos |
title_fullStr | Bubble plastic use in rats hernioplasty: Uso do plástico bolha em hernioplastias de ratos |
title_full_unstemmed | Bubble plastic use in rats hernioplasty: Uso do plástico bolha em hernioplastias de ratos |
title_short | Bubble plastic use in rats hernioplasty: Uso do plástico bolha em hernioplastias de ratos |
title_sort | bubble plastic use in rats hernioplasty: uso do plástico bolha em hernioplastias de ratos |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558621/ https://www.ncbi.nlm.nih.gov/pubmed/37809872 http://dx.doi.org/10.1016/j.heliyon.2023.e19483 |
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