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Epstein–Barr virus infection leading to multiorgan involvement in an immunocompetent man
Epstein–Barr virus (EBV) is a commonly asymptomatic widespread human herpes virus affecting over 90% of the population. It mostly originates complications like simple sore throat and infectious mononucleosis but severe manifestations are rare. Herein we report a 30‐year‐old immunocompetent man who p...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558645/ https://www.ncbi.nlm.nih.gov/pubmed/37808572 http://dx.doi.org/10.1002/ccr3.7993 |
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author | Paymannejad, Saina Shirani, Kiana Najafi, Mohammad Amin Khorvash, Farzin Shamlou, Farid |
author_facet | Paymannejad, Saina Shirani, Kiana Najafi, Mohammad Amin Khorvash, Farzin Shamlou, Farid |
author_sort | Paymannejad, Saina |
collection | PubMed |
description | Epstein–Barr virus (EBV) is a commonly asymptomatic widespread human herpes virus affecting over 90% of the population. It mostly originates complications like simple sore throat and infectious mononucleosis but severe manifestations are rare. Herein we report a 30‐year‐old immunocompetent man who presented with fever, sore throat, general weakness, and drowsiness. The diagnosis was formulated based on the positive RT‐PCR test for EBV DNA and serological detection of IgM antibody against viral capsid antigen. The patient developed severe meningoencephalitis, myocarditis, and bowel perforation and passed away after 72 days of hospitalization. |
format | Online Article Text |
id | pubmed-10558645 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-105586452023-10-08 Epstein–Barr virus infection leading to multiorgan involvement in an immunocompetent man Paymannejad, Saina Shirani, Kiana Najafi, Mohammad Amin Khorvash, Farzin Shamlou, Farid Clin Case Rep Case Report Epstein–Barr virus (EBV) is a commonly asymptomatic widespread human herpes virus affecting over 90% of the population. It mostly originates complications like simple sore throat and infectious mononucleosis but severe manifestations are rare. Herein we report a 30‐year‐old immunocompetent man who presented with fever, sore throat, general weakness, and drowsiness. The diagnosis was formulated based on the positive RT‐PCR test for EBV DNA and serological detection of IgM antibody against viral capsid antigen. The patient developed severe meningoencephalitis, myocarditis, and bowel perforation and passed away after 72 days of hospitalization. John Wiley and Sons Inc. 2023-10-06 /pmc/articles/PMC10558645/ /pubmed/37808572 http://dx.doi.org/10.1002/ccr3.7993 Text en © 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Case Report Paymannejad, Saina Shirani, Kiana Najafi, Mohammad Amin Khorvash, Farzin Shamlou, Farid Epstein–Barr virus infection leading to multiorgan involvement in an immunocompetent man |
title | Epstein–Barr virus infection leading to multiorgan involvement in an immunocompetent man |
title_full | Epstein–Barr virus infection leading to multiorgan involvement in an immunocompetent man |
title_fullStr | Epstein–Barr virus infection leading to multiorgan involvement in an immunocompetent man |
title_full_unstemmed | Epstein–Barr virus infection leading to multiorgan involvement in an immunocompetent man |
title_short | Epstein–Barr virus infection leading to multiorgan involvement in an immunocompetent man |
title_sort | epstein–barr virus infection leading to multiorgan involvement in an immunocompetent man |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558645/ https://www.ncbi.nlm.nih.gov/pubmed/37808572 http://dx.doi.org/10.1002/ccr3.7993 |
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