Cargando…

Epstein–Barr virus infection leading to multiorgan involvement in an immunocompetent man

Epstein–Barr virus (EBV) is a commonly asymptomatic widespread human herpes virus affecting over 90% of the population. It mostly originates complications like simple sore throat and infectious mononucleosis but severe manifestations are rare. Herein we report a 30‐year‐old immunocompetent man who p...

Descripción completa

Detalles Bibliográficos
Autores principales: Paymannejad, Saina, Shirani, Kiana, Najafi, Mohammad Amin, Khorvash, Farzin, Shamlou, Farid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558645/
https://www.ncbi.nlm.nih.gov/pubmed/37808572
http://dx.doi.org/10.1002/ccr3.7993
_version_ 1785117322837491712
author Paymannejad, Saina
Shirani, Kiana
Najafi, Mohammad Amin
Khorvash, Farzin
Shamlou, Farid
author_facet Paymannejad, Saina
Shirani, Kiana
Najafi, Mohammad Amin
Khorvash, Farzin
Shamlou, Farid
author_sort Paymannejad, Saina
collection PubMed
description Epstein–Barr virus (EBV) is a commonly asymptomatic widespread human herpes virus affecting over 90% of the population. It mostly originates complications like simple sore throat and infectious mononucleosis but severe manifestations are rare. Herein we report a 30‐year‐old immunocompetent man who presented with fever, sore throat, general weakness, and drowsiness. The diagnosis was formulated based on the positive RT‐PCR test for EBV DNA and serological detection of IgM antibody against viral capsid antigen. The patient developed severe meningoencephalitis, myocarditis, and bowel perforation and passed away after 72 days of hospitalization.
format Online
Article
Text
id pubmed-10558645
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-105586452023-10-08 Epstein–Barr virus infection leading to multiorgan involvement in an immunocompetent man Paymannejad, Saina Shirani, Kiana Najafi, Mohammad Amin Khorvash, Farzin Shamlou, Farid Clin Case Rep Case Report Epstein–Barr virus (EBV) is a commonly asymptomatic widespread human herpes virus affecting over 90% of the population. It mostly originates complications like simple sore throat and infectious mononucleosis but severe manifestations are rare. Herein we report a 30‐year‐old immunocompetent man who presented with fever, sore throat, general weakness, and drowsiness. The diagnosis was formulated based on the positive RT‐PCR test for EBV DNA and serological detection of IgM antibody against viral capsid antigen. The patient developed severe meningoencephalitis, myocarditis, and bowel perforation and passed away after 72 days of hospitalization. John Wiley and Sons Inc. 2023-10-06 /pmc/articles/PMC10558645/ /pubmed/37808572 http://dx.doi.org/10.1002/ccr3.7993 Text en © 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Report
Paymannejad, Saina
Shirani, Kiana
Najafi, Mohammad Amin
Khorvash, Farzin
Shamlou, Farid
Epstein–Barr virus infection leading to multiorgan involvement in an immunocompetent man
title Epstein–Barr virus infection leading to multiorgan involvement in an immunocompetent man
title_full Epstein–Barr virus infection leading to multiorgan involvement in an immunocompetent man
title_fullStr Epstein–Barr virus infection leading to multiorgan involvement in an immunocompetent man
title_full_unstemmed Epstein–Barr virus infection leading to multiorgan involvement in an immunocompetent man
title_short Epstein–Barr virus infection leading to multiorgan involvement in an immunocompetent man
title_sort epstein–barr virus infection leading to multiorgan involvement in an immunocompetent man
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558645/
https://www.ncbi.nlm.nih.gov/pubmed/37808572
http://dx.doi.org/10.1002/ccr3.7993
work_keys_str_mv AT paymannejadsaina epsteinbarrvirusinfectionleadingtomultiorganinvolvementinanimmunocompetentman
AT shiranikiana epsteinbarrvirusinfectionleadingtomultiorganinvolvementinanimmunocompetentman
AT najafimohammadamin epsteinbarrvirusinfectionleadingtomultiorganinvolvementinanimmunocompetentman
AT khorvashfarzin epsteinbarrvirusinfectionleadingtomultiorganinvolvementinanimmunocompetentman
AT shamloufarid epsteinbarrvirusinfectionleadingtomultiorganinvolvementinanimmunocompetentman