Layer‐Specific BTX‐A Delivery to the Gastric Muscularis Achieves Effective Weight Control and Metabolic Improvement (Adv. Sci. 28/2023)

Precision Gastric Paralysis In article number 2300822, Liang Peng, Jian Zhuang, Hua Meng, and co‐workers report a new system for the precise delivery and distribution of botulinum neurotoxin A (BTX‐A) in the gastric wall to achieve weight loss and metabolic improvement. This work clearly indicates t...

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Autores principales: Wang, Siqi, Wang, Yuqiong, Lin, Long, Li, Zongjie, Liu, Fengyi, Zhu, Long, Chen, Jie, Zhang, Nianrong, Cao, Xinyu, Ran, Sunman, Liu, Genzheng, Gao, Peng, Sun, Weiliang, Peng, Liang, Zhuang, Jian, Meng, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Back Cover
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558679/
http://dx.doi.org/10.1002/advs.202370194
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author Wang, Siqi
Wang, Yuqiong
Lin, Long
Li, Zongjie
Liu, Fengyi
Zhu, Long
Chen, Jie
Zhang, Nianrong
Cao, Xinyu
Ran, Sunman
Liu, Genzheng
Gao, Peng
Sun, Weiliang
Peng, Liang
Zhuang, Jian
Meng, Hua
author_facet Wang, Siqi
Wang, Yuqiong
Lin, Long
Li, Zongjie
Liu, Fengyi
Zhu, Long
Chen, Jie
Zhang, Nianrong
Cao, Xinyu
Ran, Sunman
Liu, Genzheng
Gao, Peng
Sun, Weiliang
Peng, Liang
Zhuang, Jian
Meng, Hua
author_sort Wang, Siqi
collection PubMed
description Precision Gastric Paralysis In article number 2300822, Liang Peng, Jian Zhuang, Hua Meng, and co‐workers report a new system for the precise delivery and distribution of botulinum neurotoxin A (BTX‐A) in the gastric wall to achieve weight loss and metabolic improvement. This work clearly indicates the gastric muscularis as the most favorable working site of BTX‐A for weight control, accompanied by improvement in blood glucose, liver steatosis, and gut micro boots. Meanwhile, this work suggests that the layer‐specific gastric paralysis microneedles could serve as a novel clinical approach to effectively produce a positive treatment outcome. [Image: see text]
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spelling pubmed-105586792023-10-08 Layer‐Specific BTX‐A Delivery to the Gastric Muscularis Achieves Effective Weight Control and Metabolic Improvement (Adv. Sci. 28/2023) Wang, Siqi Wang, Yuqiong Lin, Long Li, Zongjie Liu, Fengyi Zhu, Long Chen, Jie Zhang, Nianrong Cao, Xinyu Ran, Sunman Liu, Genzheng Gao, Peng Sun, Weiliang Peng, Liang Zhuang, Jian Meng, Hua Adv Sci (Weinh) Back Cover Precision Gastric Paralysis In article number 2300822, Liang Peng, Jian Zhuang, Hua Meng, and co‐workers report a new system for the precise delivery and distribution of botulinum neurotoxin A (BTX‐A) in the gastric wall to achieve weight loss and metabolic improvement. This work clearly indicates the gastric muscularis as the most favorable working site of BTX‐A for weight control, accompanied by improvement in blood glucose, liver steatosis, and gut micro boots. Meanwhile, this work suggests that the layer‐specific gastric paralysis microneedles could serve as a novel clinical approach to effectively produce a positive treatment outcome. [Image: see text] John Wiley and Sons Inc. 2023-10-06 /pmc/articles/PMC10558679/ http://dx.doi.org/10.1002/advs.202370194 Text en © 2023 Wiley‐VCH GmbH https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Back Cover
Wang, Siqi
Wang, Yuqiong
Lin, Long
Li, Zongjie
Liu, Fengyi
Zhu, Long
Chen, Jie
Zhang, Nianrong
Cao, Xinyu
Ran, Sunman
Liu, Genzheng
Gao, Peng
Sun, Weiliang
Peng, Liang
Zhuang, Jian
Meng, Hua
Layer‐Specific BTX‐A Delivery to the Gastric Muscularis Achieves Effective Weight Control and Metabolic Improvement (Adv. Sci. 28/2023)
title Layer‐Specific BTX‐A Delivery to the Gastric Muscularis Achieves Effective Weight Control and Metabolic Improvement (Adv. Sci. 28/2023)
title_full Layer‐Specific BTX‐A Delivery to the Gastric Muscularis Achieves Effective Weight Control and Metabolic Improvement (Adv. Sci. 28/2023)
title_fullStr Layer‐Specific BTX‐A Delivery to the Gastric Muscularis Achieves Effective Weight Control and Metabolic Improvement (Adv. Sci. 28/2023)
title_full_unstemmed Layer‐Specific BTX‐A Delivery to the Gastric Muscularis Achieves Effective Weight Control and Metabolic Improvement (Adv. Sci. 28/2023)
title_short Layer‐Specific BTX‐A Delivery to the Gastric Muscularis Achieves Effective Weight Control and Metabolic Improvement (Adv. Sci. 28/2023)
title_sort layer‐specific btx‐a delivery to the gastric muscularis achieves effective weight control and metabolic improvement (adv. sci. 28/2023)
topic Back Cover
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558679/
http://dx.doi.org/10.1002/advs.202370194
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