The senescent secretome drives PLVAP expression in cultured human hepatic endothelial cells to promote monocyte transmigration

Liver sinusoidal endothelial cells (LSEC) undergo significant phenotypic change in chronic liver disease (CLD), and yet the factors that drive this process and the impact on their function as a vascular barrier and gatekeeper for immune cell recruitment are poorly understood. Plasmalemma-vesicle-ass...

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Detalles Bibliográficos
Autores principales: Wilkinson, Alex L., Hulme, Samuel, Kennedy, James I., Mann, Emily R., Horn, Paul, Shepherd, Emma L., Yin, Kelvin, Zaki, Marco Y.W., Hardisty, Gareth, Lu, Wei-Yu, Rantakari, Pia, Adams, David H., Salmi, Marko, Hoare, Matthew, Patten, Daniel A., Shetty, Shishir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558774/
https://www.ncbi.nlm.nih.gov/pubmed/37810232
http://dx.doi.org/10.1016/j.isci.2023.107966

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