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Transcription factor UBF depletion in mouse cells results in downregulation of both downstream and upstream elements of the rRNA transcription network

Transcription/processing of the ribosomal RNA (rRNA) precursor, as part of ribosome biosynthesis, is intensively studied and characterized in eukaryotic cells. Here, we constructed shRNA-based mouse cell lines partially silenced for the Upstream Binding Factor UBF, the master regulator of rRNA trans...

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Detalles Bibliográficos
Autores principales:	Theophanous, Andria, Christodoulou, Andri, Mattheou, Charalambia, Sibai, Dany S., Moss, Tom, Santama, Niovi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558777/ https://www.ncbi.nlm.nih.gov/pubmed/37660911 http://dx.doi.org/10.1016/j.jbc.2023.105203

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