Cargando…

A novel multipurpose device for dataset creation and on-device immediate estimation of blood glucose level from reflection ppg

We propose a completely non-invasive and highly accurate portable blood glucose estimator, which is simple hardware that anyone, regardless of their prior experience or knowledge, can use to obtain an immediate reading of their blood sugar level. Glucose levels can be monitored in real time and disp...

Descripción completa

Detalles Bibliográficos
Autores principales: Mosaddequr, Kazi, Rahman, Tanzilur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558790/
https://www.ncbi.nlm.nih.gov/pubmed/37810055
http://dx.doi.org/10.1016/j.heliyon.2023.e19553
_version_ 1785117358525775872
author Mosaddequr, Kazi
Rahman, Tanzilur
author_facet Mosaddequr, Kazi
Rahman, Tanzilur
author_sort Mosaddequr, Kazi
collection PubMed
description We propose a completely non-invasive and highly accurate portable blood glucose estimator, which is simple hardware that anyone, regardless of their prior experience or knowledge, can use to obtain an immediate reading of their blood sugar level. Glucose levels can be monitored in real time and displayed on the device thanks to its infrared LED light source, sensor with built-in amplification unit, processing unit with blood glucose regression model, power management unit for autonomous operation, and display. The device was initially used to create a dataset of photoplethysmography (PPG) signals collected from the fingertip of 50 subjects. The extracted signal features were correlated with the subject's glucose level, which was measured at the same time using a commercial glucometer, and several regression models were constructed. The models were evaluated using signals from up to 110 subjects across three datasets, and the most optimized model was implemented in the device to predict the subject's blood glucose level solely based on PPG in real-time. The device with the built-in model has been subjected to extensive testing to gauge its efficacy. The device's clinical accuracy is encouraging. The pricey strips and needles that must be purchased along with the hardware in the conventional method will no longer be necessary with this device.
format Online
Article
Text
id pubmed-10558790
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-105587902023-10-08 A novel multipurpose device for dataset creation and on-device immediate estimation of blood glucose level from reflection ppg Mosaddequr, Kazi Rahman, Tanzilur Heliyon Research Article We propose a completely non-invasive and highly accurate portable blood glucose estimator, which is simple hardware that anyone, regardless of their prior experience or knowledge, can use to obtain an immediate reading of their blood sugar level. Glucose levels can be monitored in real time and displayed on the device thanks to its infrared LED light source, sensor with built-in amplification unit, processing unit with blood glucose regression model, power management unit for autonomous operation, and display. The device was initially used to create a dataset of photoplethysmography (PPG) signals collected from the fingertip of 50 subjects. The extracted signal features were correlated with the subject's glucose level, which was measured at the same time using a commercial glucometer, and several regression models were constructed. The models were evaluated using signals from up to 110 subjects across three datasets, and the most optimized model was implemented in the device to predict the subject's blood glucose level solely based on PPG in real-time. The device with the built-in model has been subjected to extensive testing to gauge its efficacy. The device's clinical accuracy is encouraging. The pricey strips and needles that must be purchased along with the hardware in the conventional method will no longer be necessary with this device. Elsevier 2023-09-01 /pmc/articles/PMC10558790/ /pubmed/37810055 http://dx.doi.org/10.1016/j.heliyon.2023.e19553 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Article
Mosaddequr, Kazi
Rahman, Tanzilur
A novel multipurpose device for dataset creation and on-device immediate estimation of blood glucose level from reflection ppg
title A novel multipurpose device for dataset creation and on-device immediate estimation of blood glucose level from reflection ppg
title_full A novel multipurpose device for dataset creation and on-device immediate estimation of blood glucose level from reflection ppg
title_fullStr A novel multipurpose device for dataset creation and on-device immediate estimation of blood glucose level from reflection ppg
title_full_unstemmed A novel multipurpose device for dataset creation and on-device immediate estimation of blood glucose level from reflection ppg
title_short A novel multipurpose device for dataset creation and on-device immediate estimation of blood glucose level from reflection ppg
title_sort novel multipurpose device for dataset creation and on-device immediate estimation of blood glucose level from reflection ppg
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558790/
https://www.ncbi.nlm.nih.gov/pubmed/37810055
http://dx.doi.org/10.1016/j.heliyon.2023.e19553
work_keys_str_mv AT mosaddequrkazi anovelmultipurposedevicefordatasetcreationandondeviceimmediateestimationofbloodglucoselevelfromreflectionppg
AT rahmantanzilur anovelmultipurposedevicefordatasetcreationandondeviceimmediateestimationofbloodglucoselevelfromreflectionppg
AT mosaddequrkazi novelmultipurposedevicefordatasetcreationandondeviceimmediateestimationofbloodglucoselevelfromreflectionppg
AT rahmantanzilur novelmultipurposedevicefordatasetcreationandondeviceimmediateestimationofbloodglucoselevelfromreflectionppg