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A novel multipurpose device for dataset creation and on-device immediate estimation of blood glucose level from reflection ppg
We propose a completely non-invasive and highly accurate portable blood glucose estimator, which is simple hardware that anyone, regardless of their prior experience or knowledge, can use to obtain an immediate reading of their blood sugar level. Glucose levels can be monitored in real time and disp...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558790/ https://www.ncbi.nlm.nih.gov/pubmed/37810055 http://dx.doi.org/10.1016/j.heliyon.2023.e19553 |
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author | Mosaddequr, Kazi Rahman, Tanzilur |
author_facet | Mosaddequr, Kazi Rahman, Tanzilur |
author_sort | Mosaddequr, Kazi |
collection | PubMed |
description | We propose a completely non-invasive and highly accurate portable blood glucose estimator, which is simple hardware that anyone, regardless of their prior experience or knowledge, can use to obtain an immediate reading of their blood sugar level. Glucose levels can be monitored in real time and displayed on the device thanks to its infrared LED light source, sensor with built-in amplification unit, processing unit with blood glucose regression model, power management unit for autonomous operation, and display. The device was initially used to create a dataset of photoplethysmography (PPG) signals collected from the fingertip of 50 subjects. The extracted signal features were correlated with the subject's glucose level, which was measured at the same time using a commercial glucometer, and several regression models were constructed. The models were evaluated using signals from up to 110 subjects across three datasets, and the most optimized model was implemented in the device to predict the subject's blood glucose level solely based on PPG in real-time. The device with the built-in model has been subjected to extensive testing to gauge its efficacy. The device's clinical accuracy is encouraging. The pricey strips and needles that must be purchased along with the hardware in the conventional method will no longer be necessary with this device. |
format | Online Article Text |
id | pubmed-10558790 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-105587902023-10-08 A novel multipurpose device for dataset creation and on-device immediate estimation of blood glucose level from reflection ppg Mosaddequr, Kazi Rahman, Tanzilur Heliyon Research Article We propose a completely non-invasive and highly accurate portable blood glucose estimator, which is simple hardware that anyone, regardless of their prior experience or knowledge, can use to obtain an immediate reading of their blood sugar level. Glucose levels can be monitored in real time and displayed on the device thanks to its infrared LED light source, sensor with built-in amplification unit, processing unit with blood glucose regression model, power management unit for autonomous operation, and display. The device was initially used to create a dataset of photoplethysmography (PPG) signals collected from the fingertip of 50 subjects. The extracted signal features were correlated with the subject's glucose level, which was measured at the same time using a commercial glucometer, and several regression models were constructed. The models were evaluated using signals from up to 110 subjects across three datasets, and the most optimized model was implemented in the device to predict the subject's blood glucose level solely based on PPG in real-time. The device with the built-in model has been subjected to extensive testing to gauge its efficacy. The device's clinical accuracy is encouraging. The pricey strips and needles that must be purchased along with the hardware in the conventional method will no longer be necessary with this device. Elsevier 2023-09-01 /pmc/articles/PMC10558790/ /pubmed/37810055 http://dx.doi.org/10.1016/j.heliyon.2023.e19553 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Research Article Mosaddequr, Kazi Rahman, Tanzilur A novel multipurpose device for dataset creation and on-device immediate estimation of blood glucose level from reflection ppg |
title | A novel multipurpose device for dataset creation and on-device immediate estimation of blood glucose level from reflection ppg |
title_full | A novel multipurpose device for dataset creation and on-device immediate estimation of blood glucose level from reflection ppg |
title_fullStr | A novel multipurpose device for dataset creation and on-device immediate estimation of blood glucose level from reflection ppg |
title_full_unstemmed | A novel multipurpose device for dataset creation and on-device immediate estimation of blood glucose level from reflection ppg |
title_short | A novel multipurpose device for dataset creation and on-device immediate estimation of blood glucose level from reflection ppg |
title_sort | novel multipurpose device for dataset creation and on-device immediate estimation of blood glucose level from reflection ppg |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558790/ https://www.ncbi.nlm.nih.gov/pubmed/37810055 http://dx.doi.org/10.1016/j.heliyon.2023.e19553 |
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