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Identification of region-specific splicing QTLs in human hippocampal tissue and its distinctive role in brain disorders
Alternative splicing (AS) regulation has an essential role in complex diseases. However, the AS profiles in the hippocampal (HIPPO) region of human brain are underexplored. Here, we investigated cis-acting sQTLs of HIPPO region in 264 samples and identified thousands of significant sQTLs. By enrichm...
Autores principales: | Li, Xiaoyan, Zhao, Yiran, Kong, Hui, Song, Chengcheng, Liu, Jie, Xia, Junfeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558811/ https://www.ncbi.nlm.nih.gov/pubmed/37810239 http://dx.doi.org/10.1016/j.isci.2023.107958 |
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