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Generation of 3D lung organoids from human induced pluripotent stem cells for modeling of lung development and viral infection

The lack of physiologically relevant in vitro models has hampered progress in understanding human lung development and disease. Here, we describe a protocol in which human induced pluripotent stem cells (hiPSCs) undergo stepwise differentiation into definitive endoderm (>88% population) to three-...

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Detalles Bibliográficos
Autores principales: Tiwari, Shashi Kant, Rana, Tariq M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558843/
https://www.ncbi.nlm.nih.gov/pubmed/37809493
http://dx.doi.org/10.1016/j.heliyon.2023.e19601