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Proposal of a New Conformal Factor and Normal Tissue Penalty Factor for Radiosurgery Treatments

The quality of a treatment plan is evaluated by the conformality of the prescribed isodose around the target and the homogeneity of dose distribution inside the target. Presently, to check the target volume conformality, a number of published conformity indices are in use. Most of these indices are...

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Autor principal: Murali, Venkatraman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558895/
https://www.ncbi.nlm.nih.gov/pubmed/37809184
http://dx.doi.org/10.7759/cureus.44800
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author Murali, Venkatraman
author_facet Murali, Venkatraman
author_sort Murali, Venkatraman
collection PubMed
description The quality of a treatment plan is evaluated by the conformality of the prescribed isodose around the target and the homogeneity of dose distribution inside the target. Presently, to check the target volume conformality, a number of published conformity indices are in use. Most of these indices are based on the target volume coverage by prescribed isodose, with respect to the total volume of the target. Some take into account the normal tissue covered by the prescribed isodose and suitably weigh the target coverage to evaluate conformity. In this study, for the irradiation of normal tissue by the prescription isodose, a normal tissue penalty factor is proposed and for the target conformality, a new conformal factor is proposed by applying this normal tissue penalty factor to the target coverage. The proposed conformal factor is evaluated for a few sample analytical cases and the results are compared with those obtained using the published conformity indices.
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spelling pubmed-105588952023-10-08 Proposal of a New Conformal Factor and Normal Tissue Penalty Factor for Radiosurgery Treatments Murali, Venkatraman Cureus Medical Physics The quality of a treatment plan is evaluated by the conformality of the prescribed isodose around the target and the homogeneity of dose distribution inside the target. Presently, to check the target volume conformality, a number of published conformity indices are in use. Most of these indices are based on the target volume coverage by prescribed isodose, with respect to the total volume of the target. Some take into account the normal tissue covered by the prescribed isodose and suitably weigh the target coverage to evaluate conformity. In this study, for the irradiation of normal tissue by the prescription isodose, a normal tissue penalty factor is proposed and for the target conformality, a new conformal factor is proposed by applying this normal tissue penalty factor to the target coverage. The proposed conformal factor is evaluated for a few sample analytical cases and the results are compared with those obtained using the published conformity indices. Cureus 2023-09-06 /pmc/articles/PMC10558895/ /pubmed/37809184 http://dx.doi.org/10.7759/cureus.44800 Text en Copyright © 2023, Murali et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Medical Physics
Murali, Venkatraman
Proposal of a New Conformal Factor and Normal Tissue Penalty Factor for Radiosurgery Treatments
title Proposal of a New Conformal Factor and Normal Tissue Penalty Factor for Radiosurgery Treatments
title_full Proposal of a New Conformal Factor and Normal Tissue Penalty Factor for Radiosurgery Treatments
title_fullStr Proposal of a New Conformal Factor and Normal Tissue Penalty Factor for Radiosurgery Treatments
title_full_unstemmed Proposal of a New Conformal Factor and Normal Tissue Penalty Factor for Radiosurgery Treatments
title_short Proposal of a New Conformal Factor and Normal Tissue Penalty Factor for Radiosurgery Treatments
title_sort proposal of a new conformal factor and normal tissue penalty factor for radiosurgery treatments
topic Medical Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558895/
https://www.ncbi.nlm.nih.gov/pubmed/37809184
http://dx.doi.org/10.7759/cureus.44800
work_keys_str_mv AT muralivenkatraman proposalofanewconformalfactorandnormaltissuepenaltyfactorforradiosurgerytreatments