Effect of hydrophilic polymers on the solubility and dissolution enhancement of rivaroxaban/beta-cyclodextrin inclusion complexes

BCS class II drugs exhibit low aqueous solubility and high permeability. Such drugs often have an incomplete or erratic absorption profile. This study aimed to predict the effects of β-cyclodextrin (βCD) and different hydrophilic polymers (poloxamer 188 (PXM-188), polyvinyl pyrrolidone (PVP) and sol...

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Detalles Bibliográficos
Autores principales: Khan, Waqas Haider, Asghar, Sajid, Khan, Ikram Ullah, Irfan, Muhammad, Alshammari, Abdulrahman, Riaz Rajoka, Muhammad Shahid, Munir, Rabia, Shah, Pervaiz A., Khalid, Ikrima, Razzaq, Fizza Abdul, Khalid, Syed Haroon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558906/
https://www.ncbi.nlm.nih.gov/pubmed/37809727
http://dx.doi.org/10.1016/j.heliyon.2023.e19658

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10558906/
https://www.ncbi.nlm.nih.gov/pubmed/37809727
http://dx.doi.org/10.1016/j.heliyon.2023.e19658

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