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ATF6 aggravates apoptosis in early porcine embryonic development by regulating organelle homeostasis under high-temperature conditions
Activating transcription factor 6 (ATF6), one of the three sensor proteins in the endoplasmic reticulum (ER), is an important regulator of ER stress-induced apoptosis. ATF6 resides in the ER and, upon activation, is translocated to the Golgi apparatus, where it is cleaved by site-1 protease (S1P) to...
Autores principales: | Sun, Ming-Hong, Jiang, Wen-Jie, Li, Xiao-Han, Lee, Song-Hee, Heo, Geun, Zhou, Dongjie, Chen, Zhi, Cui, Xiang-Shun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Science Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559089/ https://www.ncbi.nlm.nih.gov/pubmed/37501400 http://dx.doi.org/10.24272/j.issn.2095-8137.2023.080 |
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