GRP78 inhibitor HA15 increases the effect of Bortezomib on eradicating multiple myeloma cells through triggering endoplasmic reticulum stress

Bortezomib (BTZ), a selective proteasome inhibitor, exhibits a significant efficacy in the therapy of multiple myeloma (MM) partly through triggering endoplasmic reticulum (ER) stress-dependent apoptosis. However, sensitivity to BTZ varies greatly among patients. ER stress functions as a double-edge...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Yirong, Tao, Yuchen, Hu, Kexin, Lu, Jiahui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559159/
https://www.ncbi.nlm.nih.gov/pubmed/37809599
http://dx.doi.org/10.1016/j.heliyon.2023.e19806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559159/
https://www.ncbi.nlm.nih.gov/pubmed/37809599
http://dx.doi.org/10.1016/j.heliyon.2023.e19806

Ejemplares similares