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Fabrication of three-dimensional orthodontic force detecting brackets and preliminary clinical test for tooth movement simulation

This study aimed to develop an ultraminiature pressure sensor array to measure the force exerted on teeth. Orthodontic force plays an important role in effective, rapid, and safe tooth movement. However, owing to the lack of an adequate tool to measure the orthodontic force in vivo, it remains chall...

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Autores principales: Xie, Qianyang, Peilun, Li, Zhitao, Zhou, Guo, Bai, Ke, Sun, Xinxin, Li, Hu, Tao Tiger, Heng, Yang, Duohong, Zou, Chi, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559236/
https://www.ncbi.nlm.nih.gov/pubmed/37809553
http://dx.doi.org/10.1016/j.heliyon.2023.e19852
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author Xie, Qianyang
Peilun, Li
Zhitao, Zhou
Guo, Bai
Ke, Sun
Xinxin, Li
Hu, Tao Tiger
Heng, Yang
Duohong, Zou
Chi, Yang
author_facet Xie, Qianyang
Peilun, Li
Zhitao, Zhou
Guo, Bai
Ke, Sun
Xinxin, Li
Hu, Tao Tiger
Heng, Yang
Duohong, Zou
Chi, Yang
author_sort Xie, Qianyang
collection PubMed
description This study aimed to develop an ultraminiature pressure sensor array to measure the force exerted on teeth. Orthodontic force plays an important role in effective, rapid, and safe tooth movement. However, owing to the lack of an adequate tool to measure the orthodontic force in vivo, it remains challenging to determine the best orthodontic loading in clinical and basic research. In this study, a three-dimensional (3D) orthodontic force detection system based on piezoresistive absolute pressure sensors was designed. The 3D force sensing array was constructed using five pressure sensors on a single chip. The size of the sensor array was only 4.1 × 2.6 mm, which can be placed within the bracket base area. Based on the barometric calibration, conversion formulas for the output voltage and pressure of the five channels were constructed. Subsequently, a 3D linear mechanical simulation model of the voltage and stress distribution was established using 312 tests of the applied force in 13 operating modes. Finally, the output voltage was first converted to pressure and then to the resultant force. The 3D force-detection chip was then tested to verify the accuracy of force measurement on the teeth. Based on the test results, the average output force error was only 0.0025 N (0.7169%) (p = 0.958), and the average spatial positioning error was only 0.058 mm (p = 0.872) on the X-axis and 0.050 mm (p = 0.837) on the Y-axis. The simulation results were highly consistent with the actual force applied (intraclass correlation efficient (ICC): 0.997–1.000; p < 0.001). Furthermore, through in vivo measurements and a finite element analysis, the movement trends generated when the measured orthodontic forces that acted on the teeth were simulated. The results revealed that the device can accurately measure the orthodontic force, representing the first clinical test of an orthodontic-force monitoring system. Our study provides a hardware basis for clinical research on efficient, safe, and optimal orthodontic forces, and has considerable potential for application in monitoring the biomechanics of tooth movement.
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spelling pubmed-105592362023-10-08 Fabrication of three-dimensional orthodontic force detecting brackets and preliminary clinical test for tooth movement simulation Xie, Qianyang Peilun, Li Zhitao, Zhou Guo, Bai Ke, Sun Xinxin, Li Hu, Tao Tiger Heng, Yang Duohong, Zou Chi, Yang Heliyon Research Article This study aimed to develop an ultraminiature pressure sensor array to measure the force exerted on teeth. Orthodontic force plays an important role in effective, rapid, and safe tooth movement. However, owing to the lack of an adequate tool to measure the orthodontic force in vivo, it remains challenging to determine the best orthodontic loading in clinical and basic research. In this study, a three-dimensional (3D) orthodontic force detection system based on piezoresistive absolute pressure sensors was designed. The 3D force sensing array was constructed using five pressure sensors on a single chip. The size of the sensor array was only 4.1 × 2.6 mm, which can be placed within the bracket base area. Based on the barometric calibration, conversion formulas for the output voltage and pressure of the five channels were constructed. Subsequently, a 3D linear mechanical simulation model of the voltage and stress distribution was established using 312 tests of the applied force in 13 operating modes. Finally, the output voltage was first converted to pressure and then to the resultant force. The 3D force-detection chip was then tested to verify the accuracy of force measurement on the teeth. Based on the test results, the average output force error was only 0.0025 N (0.7169%) (p = 0.958), and the average spatial positioning error was only 0.058 mm (p = 0.872) on the X-axis and 0.050 mm (p = 0.837) on the Y-axis. The simulation results were highly consistent with the actual force applied (intraclass correlation efficient (ICC): 0.997–1.000; p < 0.001). Furthermore, through in vivo measurements and a finite element analysis, the movement trends generated when the measured orthodontic forces that acted on the teeth were simulated. The results revealed that the device can accurately measure the orthodontic force, representing the first clinical test of an orthodontic-force monitoring system. Our study provides a hardware basis for clinical research on efficient, safe, and optimal orthodontic forces, and has considerable potential for application in monitoring the biomechanics of tooth movement. Elsevier 2023-09-14 /pmc/articles/PMC10559236/ /pubmed/37809553 http://dx.doi.org/10.1016/j.heliyon.2023.e19852 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Article
Xie, Qianyang
Peilun, Li
Zhitao, Zhou
Guo, Bai
Ke, Sun
Xinxin, Li
Hu, Tao Tiger
Heng, Yang
Duohong, Zou
Chi, Yang
Fabrication of three-dimensional orthodontic force detecting brackets and preliminary clinical test for tooth movement simulation
title Fabrication of three-dimensional orthodontic force detecting brackets and preliminary clinical test for tooth movement simulation
title_full Fabrication of three-dimensional orthodontic force detecting brackets and preliminary clinical test for tooth movement simulation
title_fullStr Fabrication of three-dimensional orthodontic force detecting brackets and preliminary clinical test for tooth movement simulation
title_full_unstemmed Fabrication of three-dimensional orthodontic force detecting brackets and preliminary clinical test for tooth movement simulation
title_short Fabrication of three-dimensional orthodontic force detecting brackets and preliminary clinical test for tooth movement simulation
title_sort fabrication of three-dimensional orthodontic force detecting brackets and preliminary clinical test for tooth movement simulation
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559236/
https://www.ncbi.nlm.nih.gov/pubmed/37809553
http://dx.doi.org/10.1016/j.heliyon.2023.e19852
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