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Genetic modification regulates pathogenicity of a fowl adenovirus 4 strain after cell line adaptation (genetic mutation in FAdV-4 lowered pathogenicity)

Fowl adenovirus 4 (FAdV-4) is a major avian virus that induces fatal diseases in chicken such as, hydropericardium and hepatitis. The viral structure consists of hexon, penton, fiber-1, and fiber-2 which are associated with immunopathogenesis. In this study, we investigated the genetic modification...

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Detalles Bibliográficos
Autores principales:	Yeo, Ji-in, Lee, Rangyeon, Kim, Haneul, Ahn, Somin, Park, Jeongho, Sung, Haan Woo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559258/ https://www.ncbi.nlm.nih.gov/pubmed/37809944 http://dx.doi.org/10.1016/j.heliyon.2023.e19860

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