MiR-4649-5p acts as a tumor-suppressive microRNA in triple negative breast cancer by direct interaction with PIP5K1C, thereby potentiating growth-inhibitory effects of the AKT inhibitor capivasertib

BACKGROUND: Triple negative breast cancer (TNBC) is a particularly aggressive and difficult-to-treat subtype of breast cancer that requires the development of novel therapeutic strategies. To pave the way for such developments it is essential to characterize new molecular players in TNBC. MicroRNAs...

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Detalles Bibliográficos
Autores principales: Jonas, Katharina, Prinz, Felix, Ferracin, Manuela, Krajina, Katarina, Pasculli, Barbara, Deutsch, Alexander, Madl, Tobias, Rinner, Beate, Slaby, Ondrej, Klec, Christiane, Pichler, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559525/
https://www.ncbi.nlm.nih.gov/pubmed/37803350
http://dx.doi.org/10.1186/s13058-023-01716-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559525/
https://www.ncbi.nlm.nih.gov/pubmed/37803350
http://dx.doi.org/10.1186/s13058-023-01716-2

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