Cargando…

Effects of iron homeostasis on epigenetic age acceleration: a two-sample Mendelian randomization study

BACKGROUND: Epigenetic clocks constructed from DNA methylation patterns have emerged as excellent predictors of aging and aging-related health outcomes. Iron, a crucial element, is meticulously regulated within organisms, a phenomenon referred as iron homeostasis. Previous researches have demonstrat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Zhihao, Liu, Yi, Zhang, Shuxin, Yuan, Yunbo, Chen, Siliang, Li, Wenhao, Zuo, Mingrong, Xiang, Yufan, Li, Tengfei, Yang, Wanchun, Yang, Yuan, Liu, Yanhui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559596/ https://www.ncbi.nlm.nih.gov/pubmed/37805541 http://dx.doi.org/10.1186/s13148-023-01575-w

Ejemplares similares

Lipid metabolism-related gene signature predicts prognosis and depicts tumor microenvironment immune landscape in gliomas
por: Li, Junhong, et al.
Publicado: (2023)

Purine metabolism-related gene expression signature predicts survival outcome and indicates immune microenvironment profile of gliomas
por: Chen, Siliang, et al.
Publicado: (2022)

Preoperative Naples prognostic score is a reliable prognostic indicator for newly diagnosed glioblastoma patients
por: Li, Junhong, et al.
Publicado: (2022)

Prognostic value of cuproptosis-related genes signature and its impact on the reshaped immune microenvironment of glioma
por: Chen, Siliang, et al.
Publicado: (2022)

A novel score system based on arginine metabolism-related genes to predict prognosis, characterize immune microenvironment, and forecast response to immunotherapy in IDH-wildtype glioblastoma
por: Feng, Wentao, et al.
Publicado: (2023)

Prognostic value of lactate metabolism-related gene expression signature in adult primary gliomas and its impact on the tumor immune microenvironment
por: Wang, Zhihao, et al.
Publicado: (2022)

Impact of redox-related genes on tumor microenvironment immune characteristics and prognosis of high-grade gliomas
por: Yuan, Yunbo, et al.
Publicado: (2023)

Multiple Model Evaluation of the Masseteric-to-Facial Nerve Transfer for Reanimation of the Paralyzed Face and Quick Prognostic Prediction
por: Li, Tengfei, et al.
Publicado: (2022)

Glutamine metabolism-related genes predict prognosis and reshape tumor microenvironment immune characteristics in diffuse gliomas
por: Fan, Huanhuan, et al.
Publicado: (2023)

Prognostic significance of preoperative systemic inflammation response index in newly diagnosed glioblastoma patients underwent gross total resection: a propensity score matching analysis
por: Wang, Zhihao, et al.
Publicado: (2022)

Serine and glycine metabolism-related gene expression signature stratifies immune profiles of brain gliomas, and predicts prognosis and responses to immunotherapy
por: Chen, Siliang, et al.
Publicado: (2022)

Engrailed 2 (EN2) acts as a glioma suppressor by inhibiting tumor proliferation/invasion and enhancing sensitivity to temozolomide
por: Li, Tengfei, et al.
Publicado: (2020)

Prognosis prediction and tumor immune microenvironment characterization based on tryptophan metabolism-related genes signature in brain glioma
por: Zhang, Shuxin, et al.
Publicado: (2022)

Inhibition of mitochondrial carrier homolog 2 (MTCH2) suppresses tumor invasion and enhances sensitivity to temozolomide in malignant glioma
por: Yuan, Qiuyun, et al.
Publicado: (2021)

Different materials of cranioplasty for patients undergoing decompressive craniectomy: A protocol for systematic review and network meta-analysis
por: Yang, Wanchun, et al.
Publicado: (2021)

Prognostic Significance of Preoperative Albumin to Alkaline Phosphatase Ratio in Patients with Glioblastoma
por: Li, Junhong, et al.
Publicado: (2021)

Clinical Significance of Preoperative Fibrinogen to Albumin Ratio in Patients with Glioblastoma: A Singe Center Experience
por: Li, Junhong, et al.
Publicado: (2021)

Effects of epigenetic age acceleration on kidney function: a Mendelian randomization study
por: Pan, Yang, et al.
Publicado: (2023)

ETMM-06. ELEVATED MITOCHONDRIAL TOM20 EXPRESSION SUPPRESSES GLIOMA MALIGNANCY BY ENHANCING OXIDATIVE PHOSPHORYLATION
por: Li, Mao, et al.
Publicado: (2021)

Iron Overload Is Associated With Accelerated Progression of Osteoarthritis: The Role of DMT1 Mediated Iron Homeostasis
por: Jing, Xingzhi, et al.
Publicado: (2021)

Multiple sclerosis and breast cancer risk: a meta-analysis of observational and Mendelian randomization studies
por: Fang, Tian, et al.
Publicado: (2023)

Causal association of epigenetic aging and osteoporosis: a bidirectional Mendelian randomization study
por: Liang, Xinyu, et al.
Publicado: (2023)

Effect of genetic liability to migraine and its subtypes on breast cancer: a mendelian randomization study
por: Fang, Tian, et al.
Publicado: (2023)

The Mendelian disorders of the epigenetic machinery
por: Bjornsson, Hans Tomas
Publicado: (2015)

No evidence of a genetic causal relationship between ankylosing spondylitis and iron homeostasis: A two-sample Mendelian randomization study
por: Yang, Mingyi, et al.
Publicado: (2023)

Diet-derived antioxidants and osteoporosis: A Mendelian randomization study
por: Li, Haitao, et al.
Publicado: (2023)

Leveraging the Mendelian disorders of the epigenetic machinery to systematically map functional epigenetic variation
por: Luperchio, Teresa Romeo, et al.
Publicado: (2021)

Association between serum iron status and primary liver cancer risk: a Mendelian randomization analysis
por: Tian, Tao, et al.
Publicado: (2021)

Calcium Homeostasis and Psychiatric Disorders: A Mendelian Randomization Study
por: Jiang, Miaomiao, et al.
Publicado: (2023)

Effect of women’s fertility and sexual development on epigenetic clock: Mendelian randomization study
por: Zhang, Boxin, et al.
Publicado: (2023)

Causality between heart failure and epigenetic age: a bidirectional Mendelian randomization study
por: Zhang, Fengjun, et al.
Publicado: (2023)

Epigenetics of cognition and behavior: insights from Mendelian disorders of epigenetic machinery
por: Ng, Rowena, et al.
Publicado: (2023)

Genetic Causal Association between Iron Status and Osteoarthritis: A Two-Sample Mendelian Randomization
por: Xu, Jiawen, et al.
Publicado: (2022)

No genetic causal association between iron status and osteoporosis: A two-sample Mendelian randomization
por: Xu, Jiawen, et al.
Publicado: (2022)

Olfactory Malformations in Mendelian Disorders of the Epigenetic Machinery
por: Aleo, Sebastiano, et al.
Publicado: (2020)

Natural flavonoids disrupt bacterial iron homeostasis to potentiate colistin efficacy
por: Zhong, Zi-xing, et al.
Publicado: (2023)

Therapeutic Targeting of Cancer: Epigenetic Homeostasis
por: Yu, Xiaoyuan, et al.
Publicado: (2021)

The effect of systemic iron status on osteoarthritis: A mendelian randomization study
por: Ruan, Guangfeng, et al.
Publicado: (2023)

Prognostic Significance of the Combined Score of Plasma Fibrinogen and Neutrophil-Lymphocyte Ratio in Patients with Spontaneous Intracerebral Hemorrhage
por: Yang, Wanchun, et al.
Publicado: (2021)

Iron Homeostasis and Energy Metabolism in Obesity
por: Kim, Se Lin, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_57ckr1tbtb52qeu8468krda54h