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Shiga toxin 2 A-subunit induces mitochondrial damage, mitophagy and apoptosis via the interaction of Tom20 in Caco-2 cells

Shiga toxin type 2 (Stx2) is the primary virulence factor produced by Shiga toxin-producing enterohemorrhagic Escherichia coli (STEC), which causes epidemic outbreaks of gastrointestinal sickness and potentially fatal sequela hemolytic uremic syndrome (HUS). Most studies on Stx2-induced apoptosis ha...

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Detalles Bibliográficos
Autores principales:	Tang, Jie, Lu, Xiaoxue, Zhang, Tao, Feng, Yuyang, Xu, Qiaolin, Li, Jing, Lan, Yuanzhi, Luo, Huaxing, Zeng, Linghai, Xiang, Yuanyuan, Zhang, Yan, Li, Qian, Mao, Xuhu, Tang, Bin, Zeng, Dongzhu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559750/ https://www.ncbi.nlm.nih.gov/pubmed/37809632 http://dx.doi.org/10.1016/j.heliyon.2023.e20012

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