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Association of body mass index with asthma occurrence and persistence in adolescents: A retrospective study of NHANES (2011–2018)

OBJECTIVE: To investigate the association of body mass index (BMI) with asthma and analyze the risk factors of asthma persistence among overweight/obese adolescents and those with a high risk for obesity. METHODS: In this cross-sectional study, adolescents aged 11–17 years with complete general info...

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Autores principales: Li, Ren-jie, Wen, Ying-xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559872/
https://www.ncbi.nlm.nih.gov/pubmed/37809502
http://dx.doi.org/10.1016/j.heliyon.2023.e20092
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author Li, Ren-jie
Wen, Ying-xu
author_facet Li, Ren-jie
Wen, Ying-xu
author_sort Li, Ren-jie
collection PubMed
description OBJECTIVE: To investigate the association of body mass index (BMI) with asthma and analyze the risk factors of asthma persistence among overweight/obese adolescents and those with a high risk for obesity. METHODS: In this cross-sectional study, adolescents aged 11–17 years with complete general information and asthma diagnoses were selected from the National Health and Nutrition Examination Survey database. For adolescents without self-reported asthma, we performed matching according to age and sex at a case-to-control ratio of 1:3. Logistic regression analysis was employed to identify independent predictors of asthma occurrence followed by constructing a nomogram and comparing its efficacy to independent factors in predicting asthma occurrence. Besides, associations of BMI with asthma occurrence and persistence were evaluated. Finally, we obtained risk factors for asthma persistence in overweight/obese individuals and those at a high risk for obesity. RESULTS: Totally 753 adolescents with asthma and 2259 adolescents without asthma were included to analyze the occurrence of asthma. BMI and Hispanic Ethnicity were independent predictors of asthma occurrence and were included in nomogram construction. BMI had an efficiency comparable to that of the nomogram model in predicting asthma occurrence, which is superior to that of Hispanic Ethnicity. Of the 753 adolescents diagnosed with asthma, 464 were still diagnosed with asthma of at least a year's duration. Interestingly, BMI may have the ability to predict asthma persistence. Further, Hispanic Ethnicity and household income were significantly related to asthma occurrence among overweight/obese and high-risk obese individuals. CONCLUSIONS: High BMI could independently predict increased asthma occurrence. Additionally, BMI may play an essential role in predicting asthma persistence. This study may help improve the diagnosis and reduce the occurrence of asthma.
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spelling pubmed-105598722023-10-08 Association of body mass index with asthma occurrence and persistence in adolescents: A retrospective study of NHANES (2011–2018) Li, Ren-jie Wen, Ying-xu Heliyon Research Article OBJECTIVE: To investigate the association of body mass index (BMI) with asthma and analyze the risk factors of asthma persistence among overweight/obese adolescents and those with a high risk for obesity. METHODS: In this cross-sectional study, adolescents aged 11–17 years with complete general information and asthma diagnoses were selected from the National Health and Nutrition Examination Survey database. For adolescents without self-reported asthma, we performed matching according to age and sex at a case-to-control ratio of 1:3. Logistic regression analysis was employed to identify independent predictors of asthma occurrence followed by constructing a nomogram and comparing its efficacy to independent factors in predicting asthma occurrence. Besides, associations of BMI with asthma occurrence and persistence were evaluated. Finally, we obtained risk factors for asthma persistence in overweight/obese individuals and those at a high risk for obesity. RESULTS: Totally 753 adolescents with asthma and 2259 adolescents without asthma were included to analyze the occurrence of asthma. BMI and Hispanic Ethnicity were independent predictors of asthma occurrence and were included in nomogram construction. BMI had an efficiency comparable to that of the nomogram model in predicting asthma occurrence, which is superior to that of Hispanic Ethnicity. Of the 753 adolescents diagnosed with asthma, 464 were still diagnosed with asthma of at least a year's duration. Interestingly, BMI may have the ability to predict asthma persistence. Further, Hispanic Ethnicity and household income were significantly related to asthma occurrence among overweight/obese and high-risk obese individuals. CONCLUSIONS: High BMI could independently predict increased asthma occurrence. Additionally, BMI may play an essential role in predicting asthma persistence. This study may help improve the diagnosis and reduce the occurrence of asthma. Elsevier 2023-09-12 /pmc/articles/PMC10559872/ /pubmed/37809502 http://dx.doi.org/10.1016/j.heliyon.2023.e20092 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Article
Li, Ren-jie
Wen, Ying-xu
Association of body mass index with asthma occurrence and persistence in adolescents: A retrospective study of NHANES (2011–2018)
title Association of body mass index with asthma occurrence and persistence in adolescents: A retrospective study of NHANES (2011–2018)
title_full Association of body mass index with asthma occurrence and persistence in adolescents: A retrospective study of NHANES (2011–2018)
title_fullStr Association of body mass index with asthma occurrence and persistence in adolescents: A retrospective study of NHANES (2011–2018)
title_full_unstemmed Association of body mass index with asthma occurrence and persistence in adolescents: A retrospective study of NHANES (2011–2018)
title_short Association of body mass index with asthma occurrence and persistence in adolescents: A retrospective study of NHANES (2011–2018)
title_sort association of body mass index with asthma occurrence and persistence in adolescents: a retrospective study of nhanes (2011–2018)
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559872/
https://www.ncbi.nlm.nih.gov/pubmed/37809502
http://dx.doi.org/10.1016/j.heliyon.2023.e20092
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