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Development of double crosslinked sodium alginate/chitosan based hydrogels for controlled release of metronidazole and its antibacterial activity
Double network sodium alginate/chitosan hydrogels were prepared using calcium chloride (CaCl(2)) and glutaraldehyde as the crosslinking agents by the ionotropic interaction method for controlled metronidazole release. The effect of polymer ratios and CaCl(2) amount is investigated by the developing...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559936/ https://www.ncbi.nlm.nih.gov/pubmed/37809897 http://dx.doi.org/10.1016/j.heliyon.2023.e20144 |