Breast cancer stem cells tolerate chromosomal instability during tumor progression via c-Jun/AXL stress signaling

Chromosomal instability (CIN) is critical for tumor evolution, yet its relationship with stemness is unclear. Here, we describe CIN as a key stress induced during tumor initiation that is uniquely tolerated by breast cancer stem cells in an activated signaling state (aCSCs). While we noted elevated...

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Detalles Bibliográficos
Autores principales: Baba, Shahnawaz A., Sun, Qi, Mugisha, Samson, Labhsetwar, Shreyas, Klemke, Richard, Desgrosellier, Jay S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559946/
https://www.ncbi.nlm.nih.gov/pubmed/37809421
http://dx.doi.org/10.1016/j.heliyon.2023.e20182

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