Structural conservation of insulin/IGF signalling axis at the insulin receptors level in Drosophila and humans

The insulin-related hormones regulate key life processes in Metazoa, from metabolism to growth, lifespan and aging, through an evolutionarily conserved insulin signalling axis (IIS). In humans the IIS axis is controlled by insulin, two insulin-like growth factors, two isoforms of the insulin recepto...

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Detalles Bibliográficos
Autores principales: Viola, Cristina M., Frittmann, Orsolya, Jenkins, Huw T., Shafi, Talha, De Meyts, Pierre, Brzozowski, Andrzej M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560217/
https://www.ncbi.nlm.nih.gov/pubmed/37805602
http://dx.doi.org/10.1038/s41467-023-41862-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560217/
https://www.ncbi.nlm.nih.gov/pubmed/37805602
http://dx.doi.org/10.1038/s41467-023-41862-x

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