A hybrid register and questionnaire study of Covid-19 and post-acute sick leave in Denmark

Post-acute sick leave is an underexplored indicator of the societal burden of SARS-CoV-2. Here,  we report findings about self-reported sick leave and risk factors thereof from a hybrid survey and register study, which include 37,482 RT-PCR confirmed SARS-CoV-2 cases and 51,336 test-negative control...

Descripción completa

Detalles Bibliográficos
Autores principales: O’Regan, Elisabeth, Svalgaard, Ingrid Bech, Sørensen, Anna Irene Vedel, Spiliopoulos, Lampros, Bager, Peter, Nielsen, Nete Munk, Hansen, Jørgen Vinsløv, Koch, Anders, Ethelberg, Steen, Hviid, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560282/
https://www.ncbi.nlm.nih.gov/pubmed/37805514
http://dx.doi.org/10.1038/s41467-023-42048-1
_version_ 1785117698727870464
author O’Regan, Elisabeth
Svalgaard, Ingrid Bech
Sørensen, Anna Irene Vedel
Spiliopoulos, Lampros
Bager, Peter
Nielsen, Nete Munk
Hansen, Jørgen Vinsløv
Koch, Anders
Ethelberg, Steen
Hviid, Anders
author_facet O’Regan, Elisabeth
Svalgaard, Ingrid Bech
Sørensen, Anna Irene Vedel
Spiliopoulos, Lampros
Bager, Peter
Nielsen, Nete Munk
Hansen, Jørgen Vinsløv
Koch, Anders
Ethelberg, Steen
Hviid, Anders
author_sort O’Regan, Elisabeth
collection PubMed
description Post-acute sick leave is an underexplored indicator of the societal burden of SARS-CoV-2. Here,  we report findings about self-reported sick leave and risk factors thereof from a hybrid survey and register study, which include 37,482 RT-PCR confirmed SARS-CoV-2 cases and 51,336 test-negative controls who were tested during the index- and alpha-dominant waves. We observe that an additional 33 individuals per 1000 took substantial sick leave following acute infection compared to persons with no known history of infection, where substantial sick leave is defined as >1 month of sick leave within the period 1–9 months after the RT-PCR test date. Being female, 50–65 years, or having certain pre-existing health conditions such as obesity, chronic lung diseases, and fibromyalgia each increase risk for taking substantial sick leave. Altogether, these results may help motivate improved diagnostic and treatment options for persons living with post-Covid conditions.
format Online
Article
Text
id pubmed-10560282
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-105602822023-10-09 A hybrid register and questionnaire study of Covid-19 and post-acute sick leave in Denmark O’Regan, Elisabeth Svalgaard, Ingrid Bech Sørensen, Anna Irene Vedel Spiliopoulos, Lampros Bager, Peter Nielsen, Nete Munk Hansen, Jørgen Vinsløv Koch, Anders Ethelberg, Steen Hviid, Anders Nat Commun Article Post-acute sick leave is an underexplored indicator of the societal burden of SARS-CoV-2. Here,  we report findings about self-reported sick leave and risk factors thereof from a hybrid survey and register study, which include 37,482 RT-PCR confirmed SARS-CoV-2 cases and 51,336 test-negative controls who were tested during the index- and alpha-dominant waves. We observe that an additional 33 individuals per 1000 took substantial sick leave following acute infection compared to persons with no known history of infection, where substantial sick leave is defined as >1 month of sick leave within the period 1–9 months after the RT-PCR test date. Being female, 50–65 years, or having certain pre-existing health conditions such as obesity, chronic lung diseases, and fibromyalgia each increase risk for taking substantial sick leave. Altogether, these results may help motivate improved diagnostic and treatment options for persons living with post-Covid conditions. Nature Publishing Group UK 2023-10-07 /pmc/articles/PMC10560282/ /pubmed/37805514 http://dx.doi.org/10.1038/s41467-023-42048-1 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
O’Regan, Elisabeth
Svalgaard, Ingrid Bech
Sørensen, Anna Irene Vedel
Spiliopoulos, Lampros
Bager, Peter
Nielsen, Nete Munk
Hansen, Jørgen Vinsløv
Koch, Anders
Ethelberg, Steen
Hviid, Anders
A hybrid register and questionnaire study of Covid-19 and post-acute sick leave in Denmark
title A hybrid register and questionnaire study of Covid-19 and post-acute sick leave in Denmark
title_full A hybrid register and questionnaire study of Covid-19 and post-acute sick leave in Denmark
title_fullStr A hybrid register and questionnaire study of Covid-19 and post-acute sick leave in Denmark
title_full_unstemmed A hybrid register and questionnaire study of Covid-19 and post-acute sick leave in Denmark
title_short A hybrid register and questionnaire study of Covid-19 and post-acute sick leave in Denmark
title_sort hybrid register and questionnaire study of covid-19 and post-acute sick leave in denmark
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560282/
https://www.ncbi.nlm.nih.gov/pubmed/37805514
http://dx.doi.org/10.1038/s41467-023-42048-1
work_keys_str_mv AT oreganelisabeth ahybridregisterandquestionnairestudyofcovid19andpostacutesickleaveindenmark
AT svalgaardingridbech ahybridregisterandquestionnairestudyofcovid19andpostacutesickleaveindenmark
AT sørensenannairenevedel ahybridregisterandquestionnairestudyofcovid19andpostacutesickleaveindenmark
AT spiliopouloslampros ahybridregisterandquestionnairestudyofcovid19andpostacutesickleaveindenmark
AT bagerpeter ahybridregisterandquestionnairestudyofcovid19andpostacutesickleaveindenmark
AT nielsennetemunk ahybridregisterandquestionnairestudyofcovid19andpostacutesickleaveindenmark
AT hansenjørgenvinsløv ahybridregisterandquestionnairestudyofcovid19andpostacutesickleaveindenmark
AT kochanders ahybridregisterandquestionnairestudyofcovid19andpostacutesickleaveindenmark
AT ethelbergsteen ahybridregisterandquestionnairestudyofcovid19andpostacutesickleaveindenmark
AT hviidanders ahybridregisterandquestionnairestudyofcovid19andpostacutesickleaveindenmark
AT oreganelisabeth hybridregisterandquestionnairestudyofcovid19andpostacutesickleaveindenmark
AT svalgaardingridbech hybridregisterandquestionnairestudyofcovid19andpostacutesickleaveindenmark
AT sørensenannairenevedel hybridregisterandquestionnairestudyofcovid19andpostacutesickleaveindenmark
AT spiliopouloslampros hybridregisterandquestionnairestudyofcovid19andpostacutesickleaveindenmark
AT bagerpeter hybridregisterandquestionnairestudyofcovid19andpostacutesickleaveindenmark
AT nielsennetemunk hybridregisterandquestionnairestudyofcovid19andpostacutesickleaveindenmark
AT hansenjørgenvinsløv hybridregisterandquestionnairestudyofcovid19andpostacutesickleaveindenmark
AT kochanders hybridregisterandquestionnairestudyofcovid19andpostacutesickleaveindenmark
AT ethelbergsteen hybridregisterandquestionnairestudyofcovid19andpostacutesickleaveindenmark
AT hviidanders hybridregisterandquestionnairestudyofcovid19andpostacutesickleaveindenmark

Ejemplares similares