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Dalpiciclib and pyrotinib in women with HER2-positive advanced breast cancer: a single-arm phase II trial

CDK4/6 inhibitors have shown a synergistic effect with anti-HER2 therapy in hormone receptor (HR)-positive and HER2-positive breast cancer (BC). In this phase 2 study (NCT04293276), we aim to evaluate a dual-oral regimen of CDK4/6 inhibitor dalpiciclib combined with HER2 tyrosine kinase inhibitor py...

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Detalles Bibliográficos
Autores principales:	Yan, Min, Niu, Limin, Lv, Huimin, Zhang, Mengwei, Wang, Jing, Liu, Zhenzhen, Chen, Xiuchun, Lu, Zhenduo, Zhang, Chongjian, Zeng, Huiai, Zhao, Shengnan, Feng, Yajing, Sun, Huihui, Li, Huajun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560297/ https://www.ncbi.nlm.nih.gov/pubmed/37805496 http://dx.doi.org/10.1038/s41467-023-41955-7

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