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Cryo-EM elucidates the uroplakin complex structure within liquid-crystalline lipids in the porcine urothelial membrane

The urothelium, a distinct epithelial tissue lining the urinary tract, serves as an essential component in preserving urinary tract integrity and thwarting infections. The asymmetric unit membrane (AUM), primarily composed of the uroplakin complex, constitutes a critical permeability barrier in fulf...

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Detalles Bibliográficos
Autores principales: Yanagisawa, Haruaki, Kita, Yoshihiro, Oda, Toshiyuki, Kikkawa, Masahide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560298/
https://www.ncbi.nlm.nih.gov/pubmed/37805589
http://dx.doi.org/10.1038/s42003-023-05393-x