A Rare Case of Acute Calcium Pyrophosphate Deposition Disease Following Zoledronic Acid Infusion

Calcium pyrophosphate deposition (CPPD) disease of the joints is a form of arthritis that can present in a severely debilitating form of pseudogout. Although mostly idiopathic, pseudogout has been reported following bisphosphonate therapy in only nine cases to date with a pathophysiology that remain...

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Autores principales: Florica, Roxana, Sekh, Marta B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560398/
https://www.ncbi.nlm.nih.gov/pubmed/37814745
http://dx.doi.org/10.7759/cureus.44892
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author Florica, Roxana
Sekh, Marta B
author_facet Florica, Roxana
Sekh, Marta B
author_sort Florica, Roxana
collection PubMed
description Calcium pyrophosphate deposition (CPPD) disease of the joints is a form of arthritis that can present in a severely debilitating form of pseudogout. Although mostly idiopathic, pseudogout has been reported following bisphosphonate therapy in only nine cases to date with a pathophysiology that remains unclear. We present the case of a 59-year-old postmenopausal woman who developed the rare onset of acute polyarticular CPPD disease following zoledronic acid infusion for the treatment of osteoporosis.
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spelling pubmed-105603982023-10-09 A Rare Case of Acute Calcium Pyrophosphate Deposition Disease Following Zoledronic Acid Infusion Florica, Roxana Sekh, Marta B Cureus Internal Medicine Calcium pyrophosphate deposition (CPPD) disease of the joints is a form of arthritis that can present in a severely debilitating form of pseudogout. Although mostly idiopathic, pseudogout has been reported following bisphosphonate therapy in only nine cases to date with a pathophysiology that remains unclear. We present the case of a 59-year-old postmenopausal woman who developed the rare onset of acute polyarticular CPPD disease following zoledronic acid infusion for the treatment of osteoporosis. Cureus 2023-09-08 /pmc/articles/PMC10560398/ /pubmed/37814745 http://dx.doi.org/10.7759/cureus.44892 Text en Copyright © 2023, Florica et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Florica, Roxana
Sekh, Marta B
A Rare Case of Acute Calcium Pyrophosphate Deposition Disease Following Zoledronic Acid Infusion
title A Rare Case of Acute Calcium Pyrophosphate Deposition Disease Following Zoledronic Acid Infusion
title_full A Rare Case of Acute Calcium Pyrophosphate Deposition Disease Following Zoledronic Acid Infusion
title_fullStr A Rare Case of Acute Calcium Pyrophosphate Deposition Disease Following Zoledronic Acid Infusion
title_full_unstemmed A Rare Case of Acute Calcium Pyrophosphate Deposition Disease Following Zoledronic Acid Infusion
title_short A Rare Case of Acute Calcium Pyrophosphate Deposition Disease Following Zoledronic Acid Infusion
title_sort rare case of acute calcium pyrophosphate deposition disease following zoledronic acid infusion
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560398/
https://www.ncbi.nlm.nih.gov/pubmed/37814745
http://dx.doi.org/10.7759/cureus.44892
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