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Internal thoracic artery graft failure and recurrence of symptoms following single-vessel coronary artery bypass graft surgery
OBJECTIVES: Coronary events and disease recurrence following coronary artery bypass (CABG) surgery could derive from either failure in the internal thoracic artery (ITA) graft, failure in other conduits or progressive disease in the coronaries. We aim to estimate the contribution of ITA graft failur...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560409/ https://www.ncbi.nlm.nih.gov/pubmed/37805490 http://dx.doi.org/10.1186/s13019-023-02384-1 |
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author | Janiec, Mikael Dimberg, Axel Lindblom, Rickard P. F. |
author_facet | Janiec, Mikael Dimberg, Axel Lindblom, Rickard P. F. |
author_sort | Janiec, Mikael |
collection | PubMed |
description | OBJECTIVES: Coronary events and disease recurrence following coronary artery bypass (CABG) surgery could derive from either failure in the internal thoracic artery (ITA) graft, failure in other conduits or progressive disease in the coronaries. We aim to estimate the contribution of ITA graft failure to the recurrence of symptoms after CABG surgery. METHODS: Within the Swedish Web System for Enhancement and Development of Evidence-Based Care in Heart Disease Evaluated According to Recommended Therapies registry, we identified patients who had coronary artery bypass grafting from 1997 to 2020 with a single-vessel ITA graft bypass. Deaths, postoperative incidence of coronary angiography and the presence of a failed graft at the time of the angiography were recorded. RESULTS: The study population consisted of 1939 patients with a mean follow-up time (SD) of 17.2 (5.6) years. The cumulative incidence (95% CI) at 20 years for a first clinically-driven postoperative angiography was 38.6% (36.2–41.1). A failed ITA graft was reported in 16.4% of the angiographies. CONCLUSIONS: A substantial part of recurrent symptoms of coronary artery disease do not seem to be related to ITA failure. Disease progression in the native coronary vessels may instead be the main driver of symptom recurrence. |
format | Online Article Text |
id | pubmed-10560409 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-105604092023-10-09 Internal thoracic artery graft failure and recurrence of symptoms following single-vessel coronary artery bypass graft surgery Janiec, Mikael Dimberg, Axel Lindblom, Rickard P. F. J Cardiothorac Surg Research OBJECTIVES: Coronary events and disease recurrence following coronary artery bypass (CABG) surgery could derive from either failure in the internal thoracic artery (ITA) graft, failure in other conduits or progressive disease in the coronaries. We aim to estimate the contribution of ITA graft failure to the recurrence of symptoms after CABG surgery. METHODS: Within the Swedish Web System for Enhancement and Development of Evidence-Based Care in Heart Disease Evaluated According to Recommended Therapies registry, we identified patients who had coronary artery bypass grafting from 1997 to 2020 with a single-vessel ITA graft bypass. Deaths, postoperative incidence of coronary angiography and the presence of a failed graft at the time of the angiography were recorded. RESULTS: The study population consisted of 1939 patients with a mean follow-up time (SD) of 17.2 (5.6) years. The cumulative incidence (95% CI) at 20 years for a first clinically-driven postoperative angiography was 38.6% (36.2–41.1). A failed ITA graft was reported in 16.4% of the angiographies. CONCLUSIONS: A substantial part of recurrent symptoms of coronary artery disease do not seem to be related to ITA failure. Disease progression in the native coronary vessels may instead be the main driver of symptom recurrence. BioMed Central 2023-10-07 /pmc/articles/PMC10560409/ /pubmed/37805490 http://dx.doi.org/10.1186/s13019-023-02384-1 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Janiec, Mikael Dimberg, Axel Lindblom, Rickard P. F. Internal thoracic artery graft failure and recurrence of symptoms following single-vessel coronary artery bypass graft surgery |
title | Internal thoracic artery graft failure and recurrence of symptoms following single-vessel coronary artery bypass graft surgery |
title_full | Internal thoracic artery graft failure and recurrence of symptoms following single-vessel coronary artery bypass graft surgery |
title_fullStr | Internal thoracic artery graft failure and recurrence of symptoms following single-vessel coronary artery bypass graft surgery |
title_full_unstemmed | Internal thoracic artery graft failure and recurrence of symptoms following single-vessel coronary artery bypass graft surgery |
title_short | Internal thoracic artery graft failure and recurrence of symptoms following single-vessel coronary artery bypass graft surgery |
title_sort | internal thoracic artery graft failure and recurrence of symptoms following single-vessel coronary artery bypass graft surgery |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560409/ https://www.ncbi.nlm.nih.gov/pubmed/37805490 http://dx.doi.org/10.1186/s13019-023-02384-1 |
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