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Bilateral Avascular Necrosis of the Femoral Heads Secondary to Familial Hyperlipidemia
Avascular necrosis (AVN) is a progressive disease characterized by bone death secondary to an interruption of the relevant vascular supply. While it is most common in pediatrics and later adulthood, it can occur at any age. This case describes a previously healthy man in his mid-twenties who present...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560536/ https://www.ncbi.nlm.nih.gov/pubmed/37814725 http://dx.doi.org/10.7759/cureus.44910 |
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author | Fusillo, Thomas F Nguyen, Michael |
author_facet | Fusillo, Thomas F Nguyen, Michael |
author_sort | Fusillo, Thomas F |
collection | PubMed |
description | Avascular necrosis (AVN) is a progressive disease characterized by bone death secondary to an interruption of the relevant vascular supply. While it is most common in pediatrics and later adulthood, it can occur at any age. This case describes a previously healthy man in his mid-twenties who presented with worsening hip pain. Imaging, including X-ray and magnetic resonance, revealed severe marrow edema and early collapse of the femoral head. The patient was also found to have a severely elevated low-density lipoprotein level, leading to the diagnosis of AVN due to familial hyperlipidemia. He received a total hip arthroplasty and was started on high-intensity statin therapy. This case highlights the importance of considering AVN in the young adult population with hip pain as well as the appropriate workup and treatment. |
format | Online Article Text |
id | pubmed-10560536 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-105605362023-10-09 Bilateral Avascular Necrosis of the Femoral Heads Secondary to Familial Hyperlipidemia Fusillo, Thomas F Nguyen, Michael Cureus Orthopedics Avascular necrosis (AVN) is a progressive disease characterized by bone death secondary to an interruption of the relevant vascular supply. While it is most common in pediatrics and later adulthood, it can occur at any age. This case describes a previously healthy man in his mid-twenties who presented with worsening hip pain. Imaging, including X-ray and magnetic resonance, revealed severe marrow edema and early collapse of the femoral head. The patient was also found to have a severely elevated low-density lipoprotein level, leading to the diagnosis of AVN due to familial hyperlipidemia. He received a total hip arthroplasty and was started on high-intensity statin therapy. This case highlights the importance of considering AVN in the young adult population with hip pain as well as the appropriate workup and treatment. Cureus 2023-09-08 /pmc/articles/PMC10560536/ /pubmed/37814725 http://dx.doi.org/10.7759/cureus.44910 Text en Copyright © 2023, Fusillo et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Orthopedics Fusillo, Thomas F Nguyen, Michael Bilateral Avascular Necrosis of the Femoral Heads Secondary to Familial Hyperlipidemia |
title | Bilateral Avascular Necrosis of the Femoral Heads Secondary to Familial Hyperlipidemia |
title_full | Bilateral Avascular Necrosis of the Femoral Heads Secondary to Familial Hyperlipidemia |
title_fullStr | Bilateral Avascular Necrosis of the Femoral Heads Secondary to Familial Hyperlipidemia |
title_full_unstemmed | Bilateral Avascular Necrosis of the Femoral Heads Secondary to Familial Hyperlipidemia |
title_short | Bilateral Avascular Necrosis of the Femoral Heads Secondary to Familial Hyperlipidemia |
title_sort | bilateral avascular necrosis of the femoral heads secondary to familial hyperlipidemia |
topic | Orthopedics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560536/ https://www.ncbi.nlm.nih.gov/pubmed/37814725 http://dx.doi.org/10.7759/cureus.44910 |
work_keys_str_mv | AT fusillothomasf bilateralavascularnecrosisofthefemoralheadssecondarytofamilialhyperlipidemia AT nguyenmichael bilateralavascularnecrosisofthefemoralheadssecondarytofamilialhyperlipidemia |