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Paxillin regulates liver fibrosis via actin polymerization and ERK activation in hepatic stellate cells
Liver injury leads to fibrosis and cirrhosis. The primary mechanism underlying the fibrogenic response is the activation of hepatic stellate cells (HSCs), which are ‘quiescent’ in normal liver but become ‘activated’ after injury by transdifferentiating into extracellular matrix (ECM)-secreting myofi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560551/ https://www.ncbi.nlm.nih.gov/pubmed/37667902 http://dx.doi.org/10.1242/jcs.261122 |