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Paxillin regulates liver fibrosis via actin polymerization and ERK activation in hepatic stellate cells

Liver injury leads to fibrosis and cirrhosis. The primary mechanism underlying the fibrogenic response is the activation of hepatic stellate cells (HSCs), which are ‘quiescent’ in normal liver but become ‘activated’ after injury by transdifferentiating into extracellular matrix (ECM)-secreting myofi...

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Detalles Bibliográficos
Autores principales:	Hijazi, Nour, Shi, Zengdun, Rockey, Don C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560551/ https://www.ncbi.nlm.nih.gov/pubmed/37667902 http://dx.doi.org/10.1242/jcs.261122

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