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An inducible germ cell ablation chicken model for high-grade germline chimeras

Chicken embryos are a powerful and widely used animal model in developmental biology studies. Since the development of CRISPR technology, gene-edited chickens have been generated by transferring primordial germ cells (PGCs) into recipients after genetic modifications. However, low inheritance caused...

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Detalles Bibliográficos
Autores principales: Chen, Yi-Chen, Saito, Daisuke, Suzuki, Takayuki, Takemoto, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560566/
https://www.ncbi.nlm.nih.gov/pubmed/37665168
http://dx.doi.org/10.1242/dev.202079