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Emerging insights into ethnic-specific TP53 germline variants

The recent expansion of human genomics repositories has facilitated the discovery of novel TP53 variants in populations of different ethnic origins. Interpreting TP53 variants is a major clinical challenge because they are functionally diverse, confer highly variable predisposition to cancer (includ...

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Detalles Bibliográficos
Autores principales:	Fischer, Nicholas W, Ma, Yu-Heng Vivian, Gariépy, Jean
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560603/ https://www.ncbi.nlm.nih.gov/pubmed/37352403 http://dx.doi.org/10.1093/jnci/djad106

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