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Pre‐gerotal fat patch—A novel alternative to haemostatic agents during partial nephrectomy

OBJECTIVE: This study aimed to determine if using a pre‐gerotal fat patch at open partial nephrectomy (PN) as a haemostatic bolster is a viable alternative to using synthetic haemostatic agents. MATERIALS AND METHODS: Human Research Ethics Committee approval was obtained for audit of a prospectively...

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Autores principales: Timm, Brennan, Thomson, Alice, Bolton, Damien, Pether, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560614/
https://www.ncbi.nlm.nih.gov/pubmed/37818025
http://dx.doi.org/10.1002/bco2.264
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author Timm, Brennan
Thomson, Alice
Bolton, Damien
Pether, Michael
author_facet Timm, Brennan
Thomson, Alice
Bolton, Damien
Pether, Michael
author_sort Timm, Brennan
collection PubMed
description OBJECTIVE: This study aimed to determine if using a pre‐gerotal fat patch at open partial nephrectomy (PN) as a haemostatic bolster is a viable alternative to using synthetic haemostatic agents. MATERIALS AND METHODS: Human Research Ethics Committee approval was obtained for audit of a prospectively kept database from July 2012 to July 2021, which followed outcomes of patients who received a low‐tension pre‐gerotal fat patch renorrhaphy at open PN. Patient demographics, intraoperative measures, histological outcomes and post‐operative complications were analysed. Using a retroperitoneal approach, the peritoneum was mobilised and a vascularised pedicle of pre‐gerotal fat was rotated in the direction of the kidney. Routine definition of the hilum, clamping of the hilar vessels and dissection of mass followed. After watertight closure and haemostasis, the harvested pre‐gerotal fat patch was placed over the defect and secured using low‐tension renorrhaphy. Two‐layer closure of the abdominal wall with placement of a drain was routine. RESULTS: A total of 55 patients underwent open PN. Mean age was 60.4 (35–77) years. There were 38 men and 17 women, and 32 right and 23 left PNs. Mean mass size was 31.9 mm (10–95 mm) and collecting system was breached in 36.5% of cases. One patient (1.9%) suffered a Clavien–Dindo IIIb complication requiring return to theatre and transfusion due to a bleed from an intercostal artery. There were no renal bed bleeds, urine leaks or urine fistulas detected. Mean intraoperative blood loss was 355 mL (50–1500 mL) and mean post‐operative creatinine increased by 10.7 μmol/L (51–172 μmol/L). Mean follow up was 40.2 (4–109) months. CONCLUSION: Utilisation of an anatomical pre‐gerotal fat patch to provide pressure at the renorrhaphy site during open PN is an effective technique to assist with surgical haemostasis. This simple technique avoids the costs of haemostatic agents, whilst adding minimal operating time to procedures.
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spelling pubmed-105606142023-10-10 Pre‐gerotal fat patch—A novel alternative to haemostatic agents during partial nephrectomy Timm, Brennan Thomson, Alice Bolton, Damien Pether, Michael BJUI Compass Original Articles OBJECTIVE: This study aimed to determine if using a pre‐gerotal fat patch at open partial nephrectomy (PN) as a haemostatic bolster is a viable alternative to using synthetic haemostatic agents. MATERIALS AND METHODS: Human Research Ethics Committee approval was obtained for audit of a prospectively kept database from July 2012 to July 2021, which followed outcomes of patients who received a low‐tension pre‐gerotal fat patch renorrhaphy at open PN. Patient demographics, intraoperative measures, histological outcomes and post‐operative complications were analysed. Using a retroperitoneal approach, the peritoneum was mobilised and a vascularised pedicle of pre‐gerotal fat was rotated in the direction of the kidney. Routine definition of the hilum, clamping of the hilar vessels and dissection of mass followed. After watertight closure and haemostasis, the harvested pre‐gerotal fat patch was placed over the defect and secured using low‐tension renorrhaphy. Two‐layer closure of the abdominal wall with placement of a drain was routine. RESULTS: A total of 55 patients underwent open PN. Mean age was 60.4 (35–77) years. There were 38 men and 17 women, and 32 right and 23 left PNs. Mean mass size was 31.9 mm (10–95 mm) and collecting system was breached in 36.5% of cases. One patient (1.9%) suffered a Clavien–Dindo IIIb complication requiring return to theatre and transfusion due to a bleed from an intercostal artery. There were no renal bed bleeds, urine leaks or urine fistulas detected. Mean intraoperative blood loss was 355 mL (50–1500 mL) and mean post‐operative creatinine increased by 10.7 μmol/L (51–172 μmol/L). Mean follow up was 40.2 (4–109) months. CONCLUSION: Utilisation of an anatomical pre‐gerotal fat patch to provide pressure at the renorrhaphy site during open PN is an effective technique to assist with surgical haemostasis. This simple technique avoids the costs of haemostatic agents, whilst adding minimal operating time to procedures. John Wiley and Sons Inc. 2023-08-16 /pmc/articles/PMC10560614/ /pubmed/37818025 http://dx.doi.org/10.1002/bco2.264 Text en © 2023 The Authors. BJUI Compass published by John Wiley & Sons Ltd on behalf of BJU International Company. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Timm, Brennan
Thomson, Alice
Bolton, Damien
Pether, Michael
Pre‐gerotal fat patch—A novel alternative to haemostatic agents during partial nephrectomy
title Pre‐gerotal fat patch—A novel alternative to haemostatic agents during partial nephrectomy
title_full Pre‐gerotal fat patch—A novel alternative to haemostatic agents during partial nephrectomy
title_fullStr Pre‐gerotal fat patch—A novel alternative to haemostatic agents during partial nephrectomy
title_full_unstemmed Pre‐gerotal fat patch—A novel alternative to haemostatic agents during partial nephrectomy
title_short Pre‐gerotal fat patch—A novel alternative to haemostatic agents during partial nephrectomy
title_sort pre‐gerotal fat patch—a novel alternative to haemostatic agents during partial nephrectomy
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560614/
https://www.ncbi.nlm.nih.gov/pubmed/37818025
http://dx.doi.org/10.1002/bco2.264
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