Cargando…

Melatonin targets ferroptosis through bimodal alteration of redox environment and cellular pathways in NAFLD model

Ferroptosis is a non-conventional cellular death caused by lipid peroxide induced iron deposition. Intracellular lipid accumulation followed by generation of lipid peroxides is an hallmark of non-alcoholic fatty liver disease (NAFLD). Melatonin (MLT) is an important pineal hormone with tremendous an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Saha, Moumita, Das, Sanjib, Manna, Krishnendu, Saha, Krishna Das
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2023
Materias:	Gastrointestinal, Renal & Hepatic Systems
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560965/ https://www.ncbi.nlm.nih.gov/pubmed/37728565 http://dx.doi.org/10.1042/BSR20230128

Ejemplares similares

Small intestine resection increases oxalate and citrate transporter expression and calcium oxalate crystal formation in rat hyperoxaluric kidneys
por: Tseng, Yi-Shiou, et al.
Publicado: (2020)

Optimal blood pressure for the minimum all-cause mortality in Chinese ESRD patients on maintenance hemodialysis
por: Wang, Tao, et al.
Publicado: (2020)

Dysregulated hepcidin response to dietary iron in male mice with reduced Gnpat expression
por: Rishi, Gautam, et al.
Publicado: (2020)

Evaluation of carbon tetrachloride fraction of Actinodaphne angustifolia Nees (Lauraceae) leaf extract for antioxidant, cytotoxic, thrombolytic and antidiarrheal properties
por: Uddin, Mohammad Najim, et al.
Publicado: (2020)

Proton pump inhibitor use and mortality in patients with cirrhosis: a meta-analysis of cohort studies
por: Wu, Xiaoli, et al.
Publicado: (2020)

Emodin protects against intestinal and lung injury induced by acute intestinal injury by modulating SP-A and TLR4/NF-κB pathway
por: Qian, Jingli, et al.
Publicado: (2020)

Emodin ameliorates renal injury in BXSB mice by modulating TNF-α/ICAM-1
por: Yuan, Xinlu, et al.
Publicado: (2020)

Dexmedetomidine with sufentanil in intravenous patient-controlled analgesia for relief from postoperative pain, inflammation and delirium after esophageal cancer surgery
por: Tang, Chaoliang, et al.
Publicado: (2020)

RCAN1.4 mediates high glucose-induced matrix production by stimulating mitochondrial fission in mesangial cells
por: Chen, Hong-Min, et al.
Publicado: (2020)

MicroRNA files in the prevention of intestinal ischemia/reperfusion injury by hydrogen rich saline
por: Yao, Weifeng, et al.
Publicado: (2020)

Proteomic screening of plasma identifies potential noninvasive biomarkers associated with significant/advanced fibrosis in patients with nonalcoholic fatty liver disease
por: Hou, Wei, et al.
Publicado: (2020)

Renal damage after liver transplantation
por: Feldkamp, Thorsten, et al.
Publicado: (2020)

Cajanonic acid A regulates the ratio of Th17/Treg via inhibition of expression of IL-6 and TGF-β in insulin-resistant HepG2 cells
por: Gong, Yanfeng, et al.
Publicado: (2019)

Down-regulation of STAT3 enhanced chemokine expression and neutrophil recruitment in biliary atresia
por: Fu, Ming, et al.
Publicado: (2021)

NPHS2 gene polymorphism aggravates renal damage caused by focal segmental glomerulosclerosis with COL4A3 mutation
por: Sun, Liping, et al.
Publicado: (2021)

Association of α-fetoprotein levels with liver stiffness measurement in outpatients with chronic hepatitis B
por: Wang, Juan, et al.
Publicado: (2021)

Lactobacillus rhamnosus GG soluble mediators ameliorate early life stress-induced visceral hypersensitivity and changes in spinal cord gene expression
por: McVey Neufeld, Karen-Anne, et al.
Publicado: (2020)

Intestinal congestion and reperfusion injury: damage caused to the intestinal tract and distal organs
por: Chen, Yajing, et al.
Publicado: (2021)

The positive rates of hepatitis B surface antibody in youth after booster vaccination: a 4-year follow-up study with large sample
por: Zhu, Xia, et al.
Publicado: (2021)

Gualou Xiebai Banxia decoction ameliorates Poloxamer 407-induced hyperlipidemia
por: Luo, Mingzhu, et al.
Publicado: (2021)

Jian-Pi-Yi-Shen formula enhances perindopril inhibition of chronic kidney disease progression by activation of SIRT3, modulation of mitochondrial dynamics, and antioxidant effects
por: Liu, Xinhui, et al.
Publicado: (2021)

Brahma-related gene-1 promotes tubular senescence and renal fibrosis through Wnt/β-catenin/autophagy axis
por: Gong, Wangqiu, et al.
Publicado: (2021)

DUSP12 acts as a novel endogenous protective signal against hepatic ischemia–reperfusion damage by inhibiting ASK1 pathway
por: Boldorini, Renzo, et al.
Publicado: (2021)

Role of fatty acid transport protein 4 in metabolic tissues: insights into obesity and fatty liver disease
por: Li, Huili, et al.
Publicado: (2022)

The antioxidant and anti-inflammatory effects of Eremina desertorum snail mucin on experimentally induced intestinal inflammation and testicular damage
por: Ibrahim, Amina M., et al.
Publicado: (2022)

The pathogenesis of gut microbiota in hepatic encephalopathy by the gut–liver–brain axis
por: Zhu, Ruirui, et al.
Publicado: (2023)

Pharmacokinetic studies of hyperoside-2-hydroxypropyl-β-cyclodextrin inclusion complex and ameliorated DSS-induced colitis in mice
por: Su, Jianqing, et al.
Publicado: (2023)

HOTAIR as a diagnostic and prognostic biomarker of gastrointestinal cancers: an updated meta-analysis and bioinformatics analysis based on TCGA data
por: Yang, Jinyou, et al.
Publicado: (2023)

Brief early life angiotensin-converting enzyme inhibition attenuates the diuretic response to saline loading in sheep with solitary functioning kidney
por: McArdle, Zoe, et al.
Publicado: (2023)

Absence of gut microbiota reduces neonatal survival and exacerbates liver disease in Cyp2c70-deficient mice with a human-like bile acid composition
por: Sjöland, Wilhelm, et al.
Publicado: (2023)

Gut microbiota depletion aggravates bile acid-induced liver pathology in mice with a human-like bile acid composition
por: Verkade, Esther, et al.
Publicado: (2023)

Pharmacologic Comparison of Clinical Neutral Endopeptidase Inhibitors in a Rat Model of Acute Secretory Diarrhea
por: Griggs, David W., et al.
Publicado: (2016)

Ozone-Induced Hypertussive Responses in Rabbits and Guinea Pigs
por: Clay, Emlyn, et al.
Publicado: (2016)

Effects of Antihypertensive Agents on Intestinal Contractility in the Spontaneously Hypertensive Rat: Angiotensin Receptor System Downregulation by Losartan
por: Patten, Glen Stephen, et al.
Publicado: (2017)

Pharmacologic Profile of Naloxegol, a Peripherally Acting µ-Opioid Receptor Antagonist, for the Treatment of Opioid-Induced Constipation
por: Floettmann, Eike, et al.
Publicado: (2017)

A Pan-Cyclophilin Inhibitor, CRV431, Decreases Fibrosis and Tumor Development in Chronic Liver Disease Models
por: Kuo, Joseph, et al.
Publicado: (2019)

8-Aminoinosine and 8-Aminohypoxanthine Inhibit Purine Nucleoside Phosphorylase and Exert Diuretic and Natriuretic Activity
por: Jackson, Edwin K., et al.
Publicado: (2022)

Melatonin Suppresses NLRP3 Inflammasome Activation via TLR4/NF-κB and P2X7R Signaling in High-Fat Diet-Induced Murine NASH Model
por: Saha, Moumita, et al.
Publicado: (2022)

TEMPORAL TRENDS IN THE DETECTION RATES OF HEPATITIS B IN THE SANTA CATARINA STATE, BRAZIL
por: Marcon, Chaiana Esmeraldino Mendes, et al.
Publicado: (2014)

HEPATITIS B VACCINATION COVERAGE AND POSTVACCINATION SEROLOGIC TESTING AMONG MEDICAL STUDENTS AT A PUBLIC UNIVERSITY IN BRAZIL
por: de Souza, Eduardo Pernambuco, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_c7k4pui64glnnhs3s4618n7cjp