Model-Based Analysis of IGF-I Response, Dosing, and Monitoring for Once-Weekly Somapacitan in Children With GH Deficiency

CONTEXT: Growth hormone (GH) replacement therapy improves longitudinal growth and adult height in children with GH deficiency (GHD). GH stimulates insulin-like growth factor (IGF)-I release, the biomarker used for monitoring GH activity during treatment. OBJECTIVE: This study aims to provide model-b...

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Detalles Bibliográficos
Autores principales: Kildemoes, Rasmus J, Backeljauw, Philippe F, Højby, Michael, Blair, Joanne C, Miller, Bradley S, Mori, Jun, Lyauk, Yassine K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Clinical Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561011/
https://www.ncbi.nlm.nih.gov/pubmed/37818403
http://dx.doi.org/10.1210/jendso/bvad115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561011/
https://www.ncbi.nlm.nih.gov/pubmed/37818403
http://dx.doi.org/10.1210/jendso/bvad115

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