BCG revaccination in adults enhances pro-inflammatory markers of trained immunity along with anti-inflammatory pathways

This study characterized mechanisms of Bacille Calmette-Guérin (BCG) revaccination-induced trained immunity (TI) in India. Adults, BCG vaccinated at birth, were sampled longitudinally before and after a second BCG dose. BCG revaccination significantly elevated tumor necrosis factor alpha (TNF-α), in...

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Detalles Bibliográficos
Autores principales: Ahmed, Asma, Tripathi, Himanshu, van Meijgaarden, Krista E., Kumar, Nirutha Chetan, Adiga, Vasista, Rakshit, Srabanti, Parthiban, Chaitra, Eveline J, Sharon, D’Souza, George, Dias, Mary, Ottenhoff, Tom H.M., Netea, Mihai G., Joosten, Simone A., Vyakarnam, Annapurna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561055/
https://www.ncbi.nlm.nih.gov/pubmed/37817935
http://dx.doi.org/10.1016/j.isci.2023.107889

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