mRNA vaccine against fibroblast activation protein ameliorates murine models of inflammatory arthritis

OBJECTIVE: Synovial fibroblasts in patients with rheumatoid arthritis (RA) contribute substantially to the perpetuation of synovitis and invasion to cartilage and bone, and are potential therapeutic targets. Fibroblast activation protein (FAP) is highly expressed by RA synovial fibroblasts and the e...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaowei, Jozic, Antony, Song, Pingfang, Xu, Qiang, Shi, Xiaofei, Wang, Hong, Bishop, Lindsey, Struthers, Hillary M, Rutledge, John, Chen, Shuang, Xu, Fei, Hancock, Meaghan H, Zhu, Daocheng, Sahay, Gaurav, Chu, Cong-Qiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561064/
https://www.ncbi.nlm.nih.gov/pubmed/37818347
http://dx.doi.org/10.2478/rir-2023-0013

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