Cargando…

Massively-multiplexed epitope mapping techniques for viral antigen discovery

Following viral infection, viral antigens bind specifically to receptors on the surface of lymphocytes thereby activating adaptive immunity in the host. An epitope, the smallest structural and functional unit of an antigen, binds specifically to an antibody or antigen receptor, to serve as key sites...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Diya, Irving, Aaron T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561112/ https://www.ncbi.nlm.nih.gov/pubmed/37818363 http://dx.doi.org/10.3389/fimmu.2023.1192385

Ejemplares similares

Antibody epitope repertoire analysis enables rapid antigen discovery and multiplex serology
por: Kamath, Kathy, et al.
Publicado: (2020)

The Immune Epitope Database and Analysis Resource in Epitope Discovery and Synthetic Vaccine Design
por: Fleri, Ward, et al.
Publicado: (2017)

Editorial: Epitope Discovery and Synthetic Vaccine Design
por: Palatnik-de-Sousa, Clarisa Beatriz, et al.
Publicado: (2018)

Multiplex Screening Assay for Identifying Cytotoxic CD8(+) T Cell Epitopes
por: Poh, Chek Meng, et al.
Publicado: (2020)

Significance of Antigen and Epitope Specificity in Tuberculosis
por: Ivanyi, Juraj, et al.
Publicado: (2014)

Mapping T Cell Responses to Native and Neo-Islet Antigen Epitopes in at Risk and Type 1 Diabetes Subjects
por: Arif, Sefina, et al.
Publicado: (2021)

A Novel Approach of Identifying Immunodominant Self and Viral Antigen Cross-Reactive T Cells and Defining the Epitopes They Recognize
por: Yang, Junbao, et al.
Publicado: (2018)

Epitope Mapping of Exposed Tegument and Alimentary Tract Proteins Identifies Putative Antigenic Targets of the Attenuated Schistosome Vaccine
por: Farias, Leonardo P., et al.
Publicado: (2021)

Landscape mapping of shared antigenic epitopes and their cognate TCRs of tumor-infiltrating T lymphocytes in melanoma
por: Murata, Kenji, et al.
Publicado: (2020)

Glycosylation of bacterial antigens changes epitope patterns
por: Kern, Karolin, et al.
Publicado: (2023)

GPU-Accelerated Discovery of Pathogen-Derived Molecular Mimics of a T-Cell Insulin Epitope
por: Whalley, Thomas, et al.
Publicado: (2020)

T Cell Epitope Discovery in the Context of Distinct and Unique Indigenous HLA Profiles
por: Hensen, Luca, et al.
Publicado: (2022)

Comprehensive Evaluation of the Expressed CD8+ T Cell Epitope Space Using High-Throughput Epitope Mapping
por: Lehmann, Paul V., et al.
Publicado: (2019)

Humoral Alloimmunity in Transplantation: Relevance of HLA Epitope Antigenicity and Immunogenicity
por: Duquesnoy, René J.
Publicado: (2011)

Potential Mimicry of Viral and Pancreatic β Cell Antigens Through Non-Spliced and cis-Spliced Zwitter Epitope Candidates in Type 1 Diabetes
por: Mishto, Michele, et al.
Publicado: (2021)

Mapping epitope characteristics on carcinoembryonic antigen.
por: Harwood, P. J., et al.
Publicado: (1986)

Epitope Profiling Reveals the Critical Antigenic Determinants in SARS-CoV-2 RBD-Based Antigen
por: Jiang, Min, et al.
Publicado: (2021)

Thyroid Autoantibodies Display both “Original Antigenic Sin” and Epitope Spreading
por: McLachlan, Sandra M., et al.
Publicado: (2017)

Complexity of Viral Epitope Surfaces as Evasive Targets for Vaccines and Therapeutic Antibodies
por: Miller, Nathaniel L., et al.
Publicado: (2022)

Spatial Mapping of Myeloid Cells and Macrophages by Multiplexed Tissue Staining
por: Saylor, Joshua, et al.
Publicado: (2018)

Random-peptide libraries and antigen-fragment libraries for epitope mapping and the development of vaccines and diagnostics
por: Irving, Melita B, et al.
Publicado: (2001)

Multiplex epitope mapping using bacterial surface display reveals both linear and conformational epitopes
por: Hudson, Elton P., et al.
Publicado: (2012)

Hidden in Plain View: Discovery of Chimeric Diabetogenic CD4 T Cell Neo-Epitopes
por: Reed, Brendan K., et al.
Publicado: (2021)

Discordance Between the Predicted Versus the Actually Recognized CD8+ T Cell Epitopes of HCMV pp65 Antigen and Aleatory Epitope Dominance
por: Lehmann, Alexander A., et al.
Publicado: (2021)

The Immunodominant T-Cell Epitopes of the Mycolyl-Transferases of the Antigen 85 Complex of M. tuberculosis
por: Huygen, Kris
Publicado: (2014)

Opportunities for Antigen Discovery in Metastatic Breast Cancer
por: Sood, Ashwani K., et al.
Publicado: (2020)

Better Epitope Discovery, Precision Immune Engineering, and Accelerated Vaccine Design Using Immunoinformatics Tools
por: De Groot, Anne S., et al.
Publicado: (2020)

Innovative Strategies to Identify M. tuberculosis Antigens and Epitopes Using Genome-Wide Analyses
por: Geluk, Annemieke, et al.
Publicado: (2014)

Endogenous Antigen Presentation of MHC Class II Epitopes through Non-Autophagic Pathways
por: Leung, Carol S. K.
Publicado: (2015)

The Mechanism of Action of Antigen Processing Independent T Cell Epitopes Designed for Immunotherapy of Autoimmune Diseases
por: Shepard, Ella R., et al.
Publicado: (2021)

SEMA: Antigen B-cell conformational epitope prediction using deep transfer learning
por: Shashkova, Tatiana I., et al.
Publicado: (2022)

Mapping of viral epitopes with prokaryotic expression products
por: Lenstra, J. A., et al.
Publicado: (1990)

Revelation of Potent Epitopes Present in Unannotated ORF Antigens of SARS-CoV-2 for Epitope-Based Polyvalent Vaccine Design Using Immunoinformatics Approach
por: Uttamrao, Patil Pranita, et al.
Publicado: (2021)

Higher Throughput Methods of Identifying T Cell Epitopes for Studying Outcomes of Altered Antigen Processing and Presentation
por: Newell, Evan W.
Publicado: (2013)

Successive Immunization With Epitope-Decreasing Dengue Antigens Induced Conservative Anti-Dengue Immune Responses
por: Hou, Jue, et al.
Publicado: (2020)

Identification of CD8(+) T-cell epitope from multiple myeloma-specific antigen AKAP4
por: Ma, Ning, et al.
Publicado: (2022)

Rapid Multiplex Genotyping of 20 HLA-A(*)02:01 Restricted Minor Histocompatibility Antigens
por: Romaniuk, Dmitrii S., et al.
Publicado: (2019)

Shotgun Immunoproteomic Approach for the Discovery of Linear B-Cell Epitopes in Biothreat Agents Francisella tularensis and Burkholderia pseudomallei
por: D’haeseleer, Patrik, et al.
Publicado: (2021)

Principles of Effective and Robust Innate Immune Response to Viral Infections: A Multiplex Network Analysis
por: Huang, Yufan, et al.
Publicado: (2019)

Antibody Specific B-Cell Epitope Predictions: Leveraging Information From Antibody-Antigen Protein Complexes
por: Jespersen, Martin Closter, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_vc16hikm0n37g8nkc4hujp7s0u