Ceramide synthase 6 (CerS6) is upregulated in alcohol-associated liver disease and exhibits sex-based differences in the regulation of energy homeostasis and lipid droplet accumulation

OBJECTIVE: Alcohol-associated liver disease (ALD) is the leading cause of liver-related mortality worldwide. Current strategies to manage ALD focus largely on advanced stage disease, however, metabolic changes such as glucose intolerance are apparent at the earliest stage of alcoholic steatosis and...

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Detalles Bibliográficos
Autores principales: Jeon, Sookyoung, Scorletti, Eleonora, Dempsey, Joseph, Buyco, Delfin, Lin, Chelsea, Saiman, Yedidya, Bayen, Susovon, Harkin, Julia, Martin, Jasmin, Hooks, Royce, Ogretmen, Besim, Argemi, Josepmaria, Melo, Luma, Bataller, Ramon, Carr, Rotonya M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561121/
https://www.ncbi.nlm.nih.gov/pubmed/37714377
http://dx.doi.org/10.1016/j.molmet.2023.101804

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