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Lymph node and bone metastasis of pulmonary intestinal adenocarcinoma: A case report
Pulmonary enteric adenocarcinoma (PEAC) is a rare pathological type of lung adenocarcinoma, accounting for ~0.6% of primary lung adenocarcinoma, which has similar morphological and immunohistochemical characteristics to colorectal adenocarcinoma. Making a certain differential diagnosis of PEAC based...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561161/ https://www.ncbi.nlm.nih.gov/pubmed/37818133 http://dx.doi.org/10.3892/ol.2023.14075 |
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author | Liu, Yanbin Feng, Zeyao Wei, Xinyu Yao, Peizhuo Liu, Xuanyu Jia, Yiwei Zhang, Shuqun Yan, Wanjun |
author_facet | Liu, Yanbin Feng, Zeyao Wei, Xinyu Yao, Peizhuo Liu, Xuanyu Jia, Yiwei Zhang, Shuqun Yan, Wanjun |
author_sort | Liu, Yanbin |
collection | PubMed |
description | Pulmonary enteric adenocarcinoma (PEAC) is a rare pathological type of lung adenocarcinoma, accounting for ~0.6% of primary lung adenocarcinoma, which has similar morphological and immunohistochemical characteristics to colorectal adenocarcinoma. Making a certain differential diagnosis of PEAC based on morphological and immunohistochemical results is difficult. It is known that PEAC may metastasize to the pancreas, skin, soleus muscle and intestine, but no bone metastasis has been reported. At our department, a rare case of PEAC with bone and lymph node metastasis was previously diagnosed. The present case study reports on a 58-year-old male patient encountered at our hospital with pain in the lumbar, back and right iliac with no obvious cause. Chest CT indicated a space-occupying lesion in the left upper lung lobe, enlarged lymph nodes in the mediastinum and left lung, and partial vertebral bone destruction. Enhanced CT results indicated multiple foci of active bone metabolism in the body, while rectal colonoscopy showed no obvious abnormalities. Histopathological and immunohistochemical results after right iliac bone puncture suggested stage IV PEAC with secondary malignancies in bones, mediastinal lymph node, hilar lymph node and left supraclavicular lymph node. |
format | Online Article Text |
id | pubmed-10561161 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-105611612023-10-10 Lymph node and bone metastasis of pulmonary intestinal adenocarcinoma: A case report Liu, Yanbin Feng, Zeyao Wei, Xinyu Yao, Peizhuo Liu, Xuanyu Jia, Yiwei Zhang, Shuqun Yan, Wanjun Oncol Lett Case Report Pulmonary enteric adenocarcinoma (PEAC) is a rare pathological type of lung adenocarcinoma, accounting for ~0.6% of primary lung adenocarcinoma, which has similar morphological and immunohistochemical characteristics to colorectal adenocarcinoma. Making a certain differential diagnosis of PEAC based on morphological and immunohistochemical results is difficult. It is known that PEAC may metastasize to the pancreas, skin, soleus muscle and intestine, but no bone metastasis has been reported. At our department, a rare case of PEAC with bone and lymph node metastasis was previously diagnosed. The present case study reports on a 58-year-old male patient encountered at our hospital with pain in the lumbar, back and right iliac with no obvious cause. Chest CT indicated a space-occupying lesion in the left upper lung lobe, enlarged lymph nodes in the mediastinum and left lung, and partial vertebral bone destruction. Enhanced CT results indicated multiple foci of active bone metabolism in the body, while rectal colonoscopy showed no obvious abnormalities. Histopathological and immunohistochemical results after right iliac bone puncture suggested stage IV PEAC with secondary malignancies in bones, mediastinal lymph node, hilar lymph node and left supraclavicular lymph node. D.A. Spandidos 2023-09-27 /pmc/articles/PMC10561161/ /pubmed/37818133 http://dx.doi.org/10.3892/ol.2023.14075 Text en Copyright: © Liu et al. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
spellingShingle | Case Report Liu, Yanbin Feng, Zeyao Wei, Xinyu Yao, Peizhuo Liu, Xuanyu Jia, Yiwei Zhang, Shuqun Yan, Wanjun Lymph node and bone metastasis of pulmonary intestinal adenocarcinoma: A case report |
title | Lymph node and bone metastasis of pulmonary intestinal adenocarcinoma: A case report |
title_full | Lymph node and bone metastasis of pulmonary intestinal adenocarcinoma: A case report |
title_fullStr | Lymph node and bone metastasis of pulmonary intestinal adenocarcinoma: A case report |
title_full_unstemmed | Lymph node and bone metastasis of pulmonary intestinal adenocarcinoma: A case report |
title_short | Lymph node and bone metastasis of pulmonary intestinal adenocarcinoma: A case report |
title_sort | lymph node and bone metastasis of pulmonary intestinal adenocarcinoma: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561161/ https://www.ncbi.nlm.nih.gov/pubmed/37818133 http://dx.doi.org/10.3892/ol.2023.14075 |
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